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Julio A. Aguirre-Ghiso, Ph.D.

Calculated based on number of publications stored in Pure and citations from Scopus
Calculated based on number of publications stored in Pure and citations from Scopus
Calculated based on number of publications stored in Pure and citations from Scopus
1994 …2024

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  • 2024

    Targeting cancer cell dormancy

    Agudo, J., Aguirre-Ghiso, J. A., Bhatia, M., Chodosh, L. A., Correia, A. L. & Klein, C. A., Feb 2024, In: Nature Reviews Cancer. 24, 2, p. 97-104 8 p.

    Research output: Contribution to journal › Article › peer-review

    2 Scopus citations
  • 2023

    5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling

    Singh, D. K., Carcamo, S., Farias, E. F., Hasson, D., Zheng, W., Sun, D., Huang, X., Cheung, J., Nobre, A. R., Kale, N., Sosa, M. S., Bernstein, E. & Aguirre-Ghiso, J. A., Jun 27 2023, In: Cell Reports. 42, 6, 112560.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    3 Scopus citations

  • A PERK-Specific Inhibitor Blocks Metastatic Progression by Limiting Integrated Stress Response–Dependent Survival of Quiescent Cancer Cells

    Calvo, V., Zheng, W., Adam-Artigues, A., Staschke, K. A., Huang, X., Cheung, J. F., Nobre, A. R., Fujisawa, S., Liu, D., Fumagalli, M., Surguladze, D., Stokes, M. E., Nowacek, A., Mulvihill, M., Farias, E. F. & Aguirre-Ghiso, J. A., Dec 15 2023, In: Clinical Cancer Research. 29, 24, p. 5155-5172 18 p.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • Dormancy in Breast Cancer

    Dalla, E., Sreekumar, A., Aguirre-Ghiso, J. A. & Chodosh, L. A., Nov 2023, In: Cold Spring Harbor Perspectives in Medicine. 13, 11, a041331.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • IGF1R Inhibition Enhances the Therapeutic Effects of Gq/11 Inhibition in Metastatic Uveal Melanoma Progression

    Lapadula, D., Lam, B., Terai, M., Sugase, T., Tanaka, R., Farias, E., Kadamb, R., Lopez-Anton, M., Heine, C. C., Modasia, B., Aguirre-Ghiso, J. A., Aplin, A. E., Sato, T. & Benovic, J. L., Jan 1 2023, In: Molecular cancer therapeutics. 22, 1, p. 63-74 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations
  • 2022

    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma

    Carcamo, S., Nguyen, C. B., Grossi, E., Filipescu, D., Alpsoy, A., Dhiman, A., Sun, D., Narang, S., Imig, J., Martin, T. C., Parsons, R., Aifantis, I., Tsirigos, A., Aguirre-Ghiso, J. A., Dykhuizen, E. C., Hasson, D. & Bernstein, E., Apr 5 2022, In: Cell Reports. 39, 1, 110637.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy

    Di Martino, J. S., Nobre, A. R., Mondal, C., Taha, I., Farias, E. F., Fertig, E. J., Naba, A., Aguirre-Ghiso, J. A. & Bravo-Cordero, J. J., Jan 2022, In: Nature Cancer. 3, 1, p. 90-107 18 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    106 Scopus citations

  • MacroH2A impedes metastatic growth by enforcing a discrete dormancy program in disseminated cancer cells

    Sun, D., Singh, D. K., Carcamo, S., Filipescu, D., Khalil, B., Huang, X., Miles, B. A., Westra, W., Sproll, K. C., Hasson, D., Bernstein, E. & Aguirre-Ghiso, J. A., Dec 2022, In: Science Advances. 8, 48, eabo0876.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • Primary tumor associated macrophages activate programs of invasion and dormancy in disseminating tumor cells

    Borriello, L., Coste, A., Traub, B., Sharma, V. P., Karagiannis, G. S., Lin, Y., Wang, Y., Ye, X., Duran, C. L., Chen, X., Friedman, M., Sosa, M. S., Sun, D., Dalla, E., Singh, D. K., Oktay, M. H., Aguirre-Ghiso, J. A., Condeelis, J. S. & Entenberg, D., Dec 2022, In: Nature communications. 13, 1, 626.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    52 Scopus citations

  • Stromal changes in the aged lung induce an emergence from melanoma dormancy

    Fane, M. E., Chhabra, Y., Alicea, G. M., Maranto, D. A., Douglass, S. M., Webster, M. R., Rebecca, V. W., Marino, G. E., Almeida, F., Ecker, B. L., Zabransky, D. J., Hüser, L., Beer, T., Tang, H. Y., Kossenkov, A., Herlyn, M., Speicher, D. W., Xu, W., Xu, X., Jaffee, E. M., & 2 othersAguirre-Ghiso, J. A. & Weeraratna, A. T., Jun 9 2022, In: Nature. 606, 7913, p. 396-405 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    61 Scopus citations

  • ZFP281 drives a mesenchymal-like dormancy program in early disseminated breast cancer cells that prevents metastatic outgrowth in the lung

    Nobre, A. R., Dalla, E., Yang, J., Huang, X., Wullkopf, L., Risson, E., Razghandi, P., Anton, M. L., Zheng, W., Seoane, J. A., Curtis, C., Kenigsberg, E., Wang, J. & Aguirre-Ghiso, J. A., Oct 2022, In: Nature Cancer. 3, 10, p. 1165-1180 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations
  • 2021

    An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy

    Khalil, B. D., Sanchez, R., Rahman, T., Rodriguez-Tirado, C., Moritsch, S., Rodriguez Martinez, A., Miles, B., Farias, E., Mezei, M., Nobre, A. R., Singh, D., Kale, N., Sproll, K. C., Sosa, M. S. & Aguirre-Ghiso, J. A., Nov 23 2021, In: Journal of Experimental Medicine. 219, 1, e20210836.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations

  • Bone marrow NG2+/Nestin+ mesenchymal stem cells drive DTC dormancy via TGF-β2

    Nobre, A. R., Risson, E., Singh, D. K., Di Martino, J. S., Cheung, J. F., Wang, J., Johnson, J., Russnes, H. G., Bravo-Cordero, J. J., Birbrair, A., Naume, B., Azhar, M., Frenette, P. S. & Aguirre-Ghiso, J. A., Mar 2021, In: Nature Cancer. 2, 3, p. 327-339 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    63 Scopus citations

  • The state of Melanoma: Emergent challenges and opportunities

    Melanoma Research Foundation, May 2021, In: Clinical Cancer Research. 27, 10, p. 2678-2697 20 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    51 Scopus citations

  • Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells

    Casanova-Acebes, M., Dalla, E., Leader, A. M., LeBerichel, J., Nikolic, J., Morales, B. M., Brown, M., Chang, C., Troncoso, L., Chen, S. T., Sastre-Perona, A., Park, M. D., Tabachnikova, A., Dhainaut, M., Hamon, P., Maier, B., Sawai, C. M., Agulló-Pascual, E., Schober, M., Brown, B. D., & 7 othersReizis, B., Marron, T., Kenigsberg, E., Moussion, C., Benaroch, P., Aguirre-Ghiso, J. A. & Merad, M., Jul 22 2021, In: Nature. 595, 7868, p. 578-584 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    261 Scopus citations

  • Translating the science of cancer dormancy to the clinic

    Aguirre-Ghiso, J. A., Sep 15 2021, In: Cancer research. 81, 18, p. 4673-4675 3 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    22 Scopus citations
  • 2020

    Immobilization rapidly selects for chemoresistant ovarian cancer cells with enhanced ability to enter dormancy

    Lam, T., Aguirre-Ghiso, J. A., Geller, M. A., Aksan, A. & Azarin, S. M., Oct 1 2020, In: Biotechnology and Bioengineering. 117, 10, p. 3066-3080 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Scopus citations

  • Metabolic adaptations to MEK and CDK4/6 cotargeting in uveal melanoma

    Teh, J. L. F., Purwin, T. J., Han, A., Chua, V., Patel, P., Baqai, U., Liao, C., Bechtel, N., Sato, T., Davies, M. A., Aguirre-Ghiso, J. & Aplin, A. E., Aug 1 2020, In: Molecular cancer therapeutics. 19, 8, p. 1719-1726 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    19 Scopus citations
  • 2019

    An IRAK1–PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy

    Liu, P. H., Shah, R. B., Li, Y., Arora, A., Ung, P. M. U., Raman, R., Gorbatenko, A., Kozono, S., Zhou, X. Z., Brechin, V., Barbaro, J. M., Thompson, R., White, R. M., Aguirre-Ghiso, J. A., Heymach, J. V., Lu, K. P., Silva, J. M., Panageas, K. S., Schlessinger, A., Maki, R. G., & 3 othersSkinner, H. D., de Stanchina, E. & Sidi, S., Feb 1 2019, In: Nature Cell Biology. 21, 2, p. 203-213 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations

  • Effects of oncogenic Gαq and Gα11 inhibition by FR900359 in uveal melanoma

    Lapadula, D., Farias, E., Randolph, C. E., Purwin, T. J., McGrath, D., Charpentier, T. H., Zhang, L., Wu, S., Terai, M., Sato, T., Tall, G. G., Zhou, N., Wedegaertner, P. B., Aplin, A. E., Aguirre-Ghiso, J. & Benovic, J. L., 2019, In: Molecular Cancer Research. 17, 4, p. 963-973 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    64 Scopus citations
  • 2018

    Macrophages orchestrate breast cancer early dissemination and metastasis

    Linde, N., Casanova-Acebes, M., Sosa, M. S., Mortha, A., Rahman, A., Farias, E., Harper, K., Tardio, E., Reyes Torres, I., Jones, J., Condeelis, J., Merad, M. & Aguirre-Ghiso, J. A., Dec 1 2018, In: Nature communications. 9, 1, 21.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    295 Scopus citations

  • NR2F1 stratifies dormant disseminated tumor cells in breast cancer patients

    Borgen, E., Rypdal, M. C., Sosa, M. S., Renolen, A., Schlichting, E., Lønning, P. E., Synnestvedt, M., Aguirre-Ghiso, J. A. & Naume, B., Oct 16 2018, In: Breast Cancer Research. 20, 1, 120.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    66 Scopus citations
  • 2017

    Mer Tyrosine Kinase Regulates Disseminated Prostate Cancer Cellular Dormancy

    Cackowski, F. C., Eber, M. R., Rhee, J., Decker, A. M., Yumoto, K., Berry, J. E., Lee, E., Shiozawa, Y., Jung, Y., Aguirre-Ghiso, J. A. & Taichman, R. S., Apr 1 2017, In: Journal of Cellular Biochemistry. 118, 4, p. 891-902 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    55 Scopus citations

  • Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments

    Fluegen, G., Avivar-Valderas, A., Wang, Y., Padgen, M. R., Williams, J. K., Nobre, A. R., Calvo, V., Cheung, J. F., Bravo-Cordero, J. J., Entenberg, D., Castracane, J., Verkhusha, V., Keely, P. J., Condeelis, J. & Aguirre-Ghiso, J. A., Jan 31 2017, In: Nature Cell Biology. 19, 2, p. 120-132 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    228 Scopus citations

  • Time-lapsed, large-volume, high-resolution intravital imaging for tissue-wide analysis of single cell dynamics

    Entenberg, D., Pastoriza, J. M., Oktay, M. H., Voiculescu, S., Wang, Y., Sosa, M. S., Aguirre-Ghiso, J. & Condeelis, J., Sep 1 2017, In: Methods. 128, p. 65-77 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    36 Scopus citations
  • 2016

    Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow

    Yumoto, K., Eber, M. R., Wang, J., Cackowski, F. C., Decker, A. M., Lee, E., Nobre, A. R., Aguirre-Ghiso, J. A., Jung, Y. & Taichman, R. S., Nov 7 2016, In: Scientific reports. 6, 36520.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    113 Scopus citations

  • Cbx8 Acts Non-canonically with Wdr5 to Promote Mammary Tumorigenesis

    Chung, C. Y., Sun, Z., Mullokandov, G., Bosch, A., Qadeer, Z. A., Cihan, E., Rapp, Z., Parsons, R., Aguirre-Ghiso, J. A., Farias, E. F., Brown, B. D., Gaspar-Maia, A. & Bernstein, E., Jul 12 2016, In: Cell Reports. 16, 2, p. 472-486 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    75 Scopus citations

  • Early dissemination seeds metastasis in breast cancer

    Hosseini, H., Obradovic, M. M. S., Hoffmann, M., Harper, K. L., Sosa, M. S., Werner-Klein, M., Nanduri, L. K., Werno, C., Ehrl, C., Maneck, M., Patwary, N., Haunschild, G., Guzvic, M., Reimelt, C., Grauvogl, M., Eichner, N., Weber, F., Hartkopf, A. D., Taran, F. A., Brucker, S. Y., & 7 othersFehm, T., Rack, B., Buchholz, S., Spang, R., Meister, G., Aguirre-Ghiso, J. A. & Klein, C. A., Dec 22 2016, In: Nature. 540, 7634, p. 552-558 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    489 Scopus citations

  • In Vivo Visualization of Stromal Macrophages via label-free FLIM-based metabolite imaging

    Szulczewski, J. M., Inman, D. R., Entenberg, D., Ponik, S. M., Aguirre-Ghiso, J., Castracane, J., Condeelis, J., Eliceiri, K. W. & Keely, P. J., May 25 2016, In: Scientific reports. 6, 25086.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    56 Scopus citations

  • Mechanism of early dissemination and metastasis in Her2+ mammary cancer

    Harper, K. L., Sosa, M. S., Entenberg, D., Hosseini, H., Cheung, J. F., Nobre, R., Avivar-Valderas, A., Nagi, C., Girnius, N., Davis, R. J., Farias, E. F., Condeelis, J., Klein, C. A. & Aguirre-Ghiso, J. A., Dec 22 2016, In: Nature. 540, 7634, p. 588-592 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    376 Scopus citations
  • 2015

    Effects of p38α/β inhibition on acute lymphoblastic leukemia proliferation and survival in vivo

    Alsadeq, A., Strube, S., Krause, S., Carlet, M., Jeremias, I., Vokuhl, C., Loges, S., Aguirre-Ghiso, J. A., Trauzold, A., Cario, G., Stanulla, M., Schrappe, M. & Schewe, D. M., Dec 1 2015, In: Leukemia. 29, 12, p. 2307-2316 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • Epithelial Xbp1 is required for cellular proliferation and differentiation during mammary gland development

    Hasegawa, D., Calvo, V., Avivar-Valderas, A., Lade, A., Chou, H. I., Lee, Y. A., Farias, E. F., Aguirre-Ghiso, J. A. & Friedman, S. L., 2015, In: Molecular and cellular biology. 35, 9, p. 1543-1556 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    32 Scopus citations

  • Identification of markers that functionally define a quiescent multiple myeloma cell sub-population surviving bortezomib treatment

    Adomako, A., Calvo, V., Biran, N., Osman, K., Chari, A., Paton, J. C., Paton, A. W., Moore, K., Schewe, D. M. & Aguirre-Ghiso, J. A., May 30 2015, In: BMC Cancer. 15, 1, 444.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes

    Sosa, M. S., Parikh, F., Maia, A. G., Estrada, Y., Bosch, A., Bragado, P., Ekpin, E., George, A., Zheng, Y., Lam, H. M., Morrissey, C., Chung, C. Y., Farias, E. F., Bernstein, E. & Aguirre-Ghiso, J. A., Jan 30 2015, In: Nature communications. 6, 6170.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    225 Scopus citations

  • Origin and interpretation of cancer transcriptome profiling: The essential role of the stroma in determining prognosis and drug resistance

    Goossens, N., Hoshida, Y. & Aguirre-Ghiso, J. A., Nov 2015, In: EMBO Molecular Medicine. 7, 11, p. 1385-1387 3 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Scopus citations

  • The in ovo chick chorioallantoic membrane (CAM) assay as an efficient xenograft model of hepatocellular carcinoma

    Li, M., Pathak, R. R., Lopez-Rivera, E., Friedman, S. L., Aguirre-Ghiso, J. A. & Sikora, A. G., Oct 9 2015, In: Journal of Visualized Experiments. 2015, 104, e52411.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    59 Scopus citations
  • 2014

    Characterization of single disseminated prostate cancer cells reveals tumor cell heterogeneity and identifies dormancy associated pathways

    Chéry, L., Lam, H. M., Coleman, I., Lakely, B., Coleman, R., Larson, S., Aguirre-Ghiso, J. A., Xia, J., Gulati, R., Nelson, P. S., Montgomery, B., Lange, P., Snyder, L. A., Vessella, R. L. & Morrissey, C., 2014, In: Oncotarget. 5, 20, p. 9939-9951 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    79 Scopus citations

  • Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2

    Lopez-Rivera, E., Jayaraman, P., Parikh, F., Davies, M. A., Ekmekcioglu, S., Izadmehr, S., Milton, D. R., Chipuk, J. E., Grimm, E. A., Estrada, Y., Aguirre-Ghiso, J. & Sikora, A. G., Feb 15 2014, In: Cancer research. 74, 4, p. 1067-1078 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    87 Scopus citations

  • Integration of microenvironmental and stress signaling antagonizes colorectal cancer progression

    Linde, N., Sosa, M. S. & Aguirre-Ghiso, J. A., Aug 18 2014, In: EMBO Journal. 33, 16, p. 1737-1739 3 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations
  • 2013

    A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α

    Begley, U., Sosa, M. S., Avivar-Valderas, A., Patil, A., Endres, L., Estrada, Y., Chan, C. T. Y., Su, D., Dedon, P. C., Aguirre-Ghiso, J. A. & Begley, T., Mar 2013, In: EMBO Molecular Medicine. 5, 3, p. 366-383 18 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    88 Scopus citations

  • Metastasis awakening: Targeting dormant cancer

    Aguirre-Ghiso, J. A., Bragado, P. & Sosa, M. S., Mar 2013, In: Nature Medicine. 19, 3, p. 276-277 2 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    80 Scopus citations

  • Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK

    Avivar-Valderas, A., Bobrovnikova-Marjon, E., Alan Diehl, J., Bardeesy, N., Debnath, J. & Aguirre-Ghiso, J. A., Oct 10 2013, In: Oncogene. 32, 41, p. 4932-4940 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    120 Scopus citations

  • TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling

    Bragado, P., Estrada, Y., Parikh, F., Krause, S., Capobianco, C., Farina, H. G., Schewe, D. M. & Aguirre-Ghiso, J. A., Nov 2013, In: Nature Cell Biology. 15, 11, p. 1351-1361 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    356 Scopus citations
  • 2012

    Analysis of marker-defined HNSCC subpopulations reveals a dynamic regulation of tumor initiating properties

    Bragado, P., Estrada, Y., Sosa, M. S., Avivar-Valderas, A., Cannan, D., Genden, E., Teng, M., Ranganathan, A. C., Wen, H. C., Kapoor, A., Bernstein, E. & Aguirre-Ghiso, J. A., Jan 20 2012, In: PloS one. 7, 1, e29974.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    25 Scopus citations

  • Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer

    Kim, R. S., Avivar-Valderas, A., Estrada, Y., Bragado, P., Sosa, M. S., Aguirre-Ghiso, J. A. & Segall, J. E., Apr 18 2012, In: PloS one. 7, 4, e35569.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    144 Scopus citations

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J. U., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L., Alegre-Abarrategui, J., & 1,249 othersAleo, M. F. R., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. 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    Research output: Contribution to journal › Article › peer-review

    2889 Scopus citations

  • p38α mediates cell survival in response to oxidative stress via induction of antioxidant genes: Effect on the p70S6K pathway

    Gutiérrez-Uzquiza, Á., Arechederra, M., Bragado, P., Aguirre-Ghiso, J. A. & Porras, A., Jan 20 2012, In: Journal of Biological Chemistry. 287, 4, p. 2632-2642 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    111 Scopus citations

  • Prognostic significance of p16 in locoregionally advanced head and neck cancer treated with concurrent 5-fluorouracil, hydroxyurea, cetuximab and intensity-modulated radiation therapy

    Tong, C. C. L., Lau, K. H. V., Rivera, M., Cannan, D., Aguirre-Ghiso, J., Sikora, A. G., Gupta, V., Forsythe, K., Ko, E. C., Misiukiewicz, K., Gurudutt, V., Teng, M. S., Packer, S. H., Genden, E. M. & Kao, J., May 2012, In: Oncology reports. 27, 5, p. 1580-1586 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations
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    Autophagy and tumor cell dormancy in head and neck cancer

    Jang, D. W., Avivar-Valderas, A., Banach, A. & Aguirre-Ghiso, J., 2011, In: Laryngoscope. 121, SUPPL. 4, p. S125

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • Bortezomib enhances the efficacy of fulvestrant by amplifying the aggregation of the estrogen receptor, which leads to a proapoptotic unfolded protein response

    Ishii, Y., Papa, L., Bahadur, U., Yue, Z., Aguirre-Ghiso, J., Shioda, T., Waxman, S. & Germain, D., Apr 15 2011, In: Clinical Cancer Research. 17, 8, p. 2292-2300 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations