Biochemistry

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  • Research project

    Broadly Protective Bispecific Antibodies for Treatment of Ebola Virus Disease

    Aman, J. M. & Lai, J. R.

    7/1/17 → 6/30/21

    Project: Research project

  • Engineering Sortase Variants for Intracellular and Cell Surface Labeling

    Levy, M.

    9/30/09 → 8/31/15

    Project: Research project

  • AN UNDULATOR RESOURCE FOR STRUCTURAL BIOLOGY

    Almo, S. C., Ealick, S., Quiocho, F., Schlessinger, J., Cerione, R. A., Clardy, J. O. N., Lippard, S., Deacon, A., Capel, M., Xavier, L., Nikolov, D., Yaffe, M., Misono, K., Golden, B. L., Ogata, C., Shapiro, L., Wang, J., Drennan, C., Baker, T., Crane, B., Wimberly, B., Pavletich, N., Eck, M., Steitz, T. A., Verdine, G., Sauer, R., Rapoport, T., Harrison, S. C., Fait, J., Nielsen, C., Mathews, F. S., Rajashankar, K., Breslow, E., Von Dreele, R., Miller, K., Decamilli, P., Phillips, G. N., Stauffacher, C., Keenan, R., Kang, C., Kissinger, C., Cabral, J., Scheraga, H. A., Dealwis, C., Brunzelle, J., Lawrence, C. M., Strobel, S., Tong, H., Petsko, G., Chen, J. U. E., Rongbao, L., Xiaolin, H., Blobel, G., Anderson, W., Furie, B., Malhotra, A., Hong, L., Howard, A. J., Hong, Y., Bartel, D., Sanders, D., Darst, S., Reinisch, K., Tong, L., Patel, D., Sicheri, F., Wu, H. A. O., Hendrickson, W. A., Schwartz, T., Gaudet, R., Ling, H., Lima, C., Mathews, S., Capel, M. S., Kissinger, C. R., Berger, J., Samanta, U., Jianhua, F., Kirchhausen, T. O. M., Morais-Cabral, J., Aaron, J., Taylor, A., Cerione, R. A., Clardy, J. O. N., Abramson, J., Cantley, L. C., Ellenberger, T., Pyle, A. M., Fan, Q., Modis, Y., Lovell, S., D'Aquino Ruiz, J. A., Brunger, A. T., De Camilli, P., Geiger, J., Sakmar, T., Goldberg, J., Caffrey, M. D., Santarsiero, B. D., Hogle, J., Wagner, G., H Eric, X., Fromme, J. C., Lacy, D. B., Anjana, R., Hunt, J., Feigon, J., Sondermann, H., Lippard, S. J., Loll, P., Jardetzky, T., Perozo, E., Dong, Z., Spiller, B., Eisenberg, D., Tahirov, T., Tanner, J., Edward, Y., Stenkamp, R., Schulman, B., Walker, S., Blacklow, S., Zhou, M., Ailong, K., Springer, T., Kent, S., Yeates, T., MacKinnon, R., Song, T., Laronde, N., Xiong, Y., Christianson, D., Keating, A., Cate, J., Gouaux, J. E., Aggarwal, A. K., Jeruzalmi, D., Decamilli, P., Heldwein, E., Bochkarev, A., Garman, S. C., Vivien, Y., van Den Berg, B., Yuxin, M., Murphy, F., Shuman, S., Kamtekar, S., Nimigean, C., Silverstein, R. O. Y., Muesar, T., Yong-Hwan, L., Rajashankar, K., Sukumar, N., Hur, S. U. N., Khan, A., Rongsheng, J., Roux, B., Jogl, G., Nikolov, D., Ha, Y. A., Braddock, D., Aihara, H., Strobel, S., Dunham, C., Herr, A., Hart, P., Fitzpatrick, P. F., Hardy, J., Degrado, W., Luecke, H., Fang, L., Sthanam, N., Newcomer, M. E., Feng, G., Hazen, S., Johnson, R., Baxter, J., Dealwis, C., Deivanayagam, C. C. S., Modis, Y., Choe, J., Wucherpfennig, K., Chuan, H., Koide, S., Mancia, F., Lemmon, M. A., Lewis, M., Walter, M., Shapiro, L., Baker, B., Goldberg, J., Santarsiero, B. D., Hogle, J., Chen, B., Asojo, O. A., Joseph, H., Hogbom, M., Konigsberg, W., Bhyravbhatla, B., van Duyne, G., Anjana, R., Ploegh, H., Dauter, Z., Agris, P., Sazinsky, M., Toor, N. S., Cheng, X., Cerione, R. A., Clardy, J. O. N., Mathews, F. S., Scheraga, H. A., Chen, J. U. E., Howard, A. J., Wu, H. A. O., Hendrickson, W. A., Capel, M. S., Kirchhausen, T. O. M., Cerione, R. A., Clardy, J. O. N., Fromme, J. C., Brunger, A. T., Cantley, L. C., Caffrey, M. D., Lippard, S. J., Aggarwal, A. K., Garman, S. C., Silverstein, R. O. Y., Hur, S. U. N., Ha, Y. A., Hart, P., Fitzpatrick, P. F., Newcomer, M. E. & Lemmon, M. A.

    6/15/01 → 3/31/13

    Project: Research project

  • NYSGXRC:A Large Scale Center for the PSI

    Almo, S. C., Sali, A., Lima, C., Shapiro, L., Swaminathan, S. & Burley, S. K.

    7/1/05 → 6/30/11

    Project: Research project

  • Function and Mechanism of Viperin, a radical SAM antiviral protein

    Almo, S. C.

    6/26/17 → 5/31/19

    Project: Research project

  • PROFILIN--STRUCTURE/FUNCTION RELATIONSHIPS

    Almo, S. C.

    9/30/95 → 4/30/05

    Project: Research project

  • COLLABORATIVE CENTER FOR AN ENZYME FUNCTION INITIATIVE

    Almo, S. C., Jacobson, M., Cronan, J. E., Gerlt, J. & Cronan, J. E.

    5/20/10 → 4/30/17

    Project: Research project

  • STRUCTURAL BIOLOGY OF THE ALLERGIC RESPONSE

    Almo, S. C.

    3/1/98 → 2/29/04

    Project: Research project

  • Protein/Structure Core

    Almo, S. C.

    National Institute of General Medical Sciences

    7/1/16 → 4/30/21

    Project: Research project

  • Core E: Protein

    Gerlt, J. A. & Almo, S. C.

    National Institute of General Medical Sciences

    5/20/10 → 4/30/16

    Project: Research project

  • DETECTING AND RESPONDING TO MISFOLDED PROTEIN BURDENS IN AGING CELLS

    Snapp, E. L. & Schmidt, M.

    National Institutes of Health

    9/15/08 → 8/31/10

    Project: Research project

  • PROTON-DETECTED HETERONUCLEAR NMR SPECTROSCOPY

    Cowburn, D.

    1/1/90 → 1/1/90

    Project: Research project

  • Signaling and Motility Assays

    Bresnick, A. R.

    National Cancer Institute

    6/1/09 → 5/31/13

    Project: Research project

  • MOTILITY AND INVASION

    Condeelis, J. S., Backer, J. M., Bresnick, A. R., Pollard, J. W., Segall, J. E. & Stanley, R. E.

    National Cancer Institute

    6/1/03 → 5/31/20

    Project: Research project

  • Dissecting the roles of protein O-GlcNAcylation in Toxoplasma gondii

    Wu, P. & Kim, K.

    8/12/13 → 7/31/15

    Project: Research project

  • REGULATION OF ADENINE NUCLEOTIDE POOLS

    Schramm, V. L. & Schramm, V. L.

    12/31/89 → 11/30/93

    Project: Research project

  • FE(III) COMPLEXES OF TRANSFERRIN

    Villafranca, J., Cammack, R., Benkovic, S., Aisen, P., Mildvan, A., Mims, W., Kozarich, J., Joseph, S., Lippai, I., Tipton, P., Frank, H., Dooley, D., Lawrence, Q., Ettinger, M., Scholes, C., McMillin, D., Palmer, G., Banerjee, R., [No Value], D. E., Stafford, D., Janson, E. D., Shanklin, J., Wittaker, J., Schramm, V. L., Danzinger, R., Walter, P., Guajardo, G., Chan, J. O. N., Wang, W., Singel, D., Caradonna, J., Sinclair, P., Friedman, J., Mason, R., Kamp, N., Goutermann, M., Fabry, M., Narasimhulu, S., Armstrong, W., Scholes, C. P., Stegeman, J., Tapan, D., Britt, D., Ohnishi, T., Danzinger, R., Zweier, J. L., Gerfen, G. J., Shaka, O., Baker, T., Brewer, F., Avdievich, N., Michael, D., Astroff, N., Stubbe, J., Tsuneshige, A., Clarkson, R., Krzystek, Y., Chance, M., Klein, M., Ming, L., Sheik, A., Wirt, M., Wong, K., Vieso, V., Licht, S., Mcdermott, A. M. Y., Zhang, C., Belford, L., Coffino, A., Beltramini, M., Crowder, M., Marcinkeviciene, J., Valentine, J., Sands, R., Nersissian, A., Klinman, J., Dyson, H. J., Caroline Caroline, L., Bender, C., Colaneri, M., Fee, J., Peisach, J., Magliozzo, R., Bowman, M., Sumuni, R., Gluck, M., Ranney, H., Frank, H., Villafranca, J., [No Value], D. E., Janson, E. D., Schramm, V. L., Danzinger, R., Chan, J. O. N., Scholes, C. P., Gerfen, G. J., Stubbe, J., Tsuneshige, A., Clarkson, R., Krzystek, Y., Chance, M., Klein, M., Ming, L., Sheik, A., Wirt, M., Wong, K., Vieso, V., Licht, S., Mcdermott, A. M. Y., Zhang, C., Belford, L., Coffino, A., Beltramini, M., Crowder, M., Marcinkeviciene, J., Valentine, J., Sands, R., Nersissian, A., Klinman, J., Dyson, H. J., Caroline Caroline, L., Bender, C., Colaneri, M., Fee, J., Peisach, J., Magliozzo, R., Bowman, M., Sumuni, R., Gluck, M., Ranney, H., Schramm, V. L., Brewer, C. F. & Gerfen, G. J.

    1/1/01 → 4/30/00

    Project: Research project

  • Applications of Click Chemistry in Glycobiology

    Wu, P.

    National Institutes of Health

    4/15/07 → 5/31/12

    Project: Research project

  • Allosteric inhibitors targeting oncogenic BRAF V600E dimers

    Gavathiotis, E.

    12/1/19 → 11/30/21

    Project: Research project

  • Console and probe upgrade for 600 MHz NMR

    Cowburn, D. & Rose, S. A.

    7/1/14 → 6/30/15

    Project: Research project

  • Chemoenzymatic methods for the detection of cell-surface glycans

    Wu, P.

    National Institutes of Health

    8/15/15 → 7/31/19

    Project: Research project

  • Signaling, Motility and TEM Assays

    Bresnick, A. R.

    National Cancer Institute

    6/1/14 → 5/31/18

    Project: Research project

  • Regulation of Histone Chaperone Function by Glutamylation

    Shechter, D.

    1/1/20 → 12/31/21

    Project: Research project

  • EXPRESSION CONTROL OF YEAST GLUCOAMYLASE GENES

    Willis, I. M. & MARMUR, J.

    National Institute of General Medical Sciences

    5/1/92 → 4/30/95

    Project: Research project

  • MAF1 Function and Metabolic Inefficiency

    Willis, I. M.

    9/21/16 → 7/31/21

    Project: Research project

  • Novel Strategies for the Discovery of Microbial Metabolic Pathways

    Gerlt, J. A., Almo, S. C. & Jacobson, M. P.

    6/15/16 → 4/30/21

    Project: Research project

  • Chemical Synthesis

    Blanchard, J. J. S. & Blanchard, J. S.

    National Cancer Institute

    7/1/19 → 6/30/22

    Project: Research project

  • Allosteric inhibitors targeting oncogenic BRAF V600E dimers

    Gavathiotis, E.

    National Cancer Institute

    12/1/19 → 11/30/23

    Project: Research project

  • Consortium for Immunotherapeutics Against Viral Hemorrhagic Fevers

    Saphire, E. O., Chandran, K., Garry, R. F., Lai, J. R. & Zeitlin, L.

    3/15/14 → 6/28/19

    Project: Research project

  • MECHANISM OF PEP CARBOXYKINASE AND PYRUVATE CARBOXYLASE

    Schramm, V. L. & Schramm, V. L.

    12/31/89 → 3/31/92

    Project: Research project

  • Chemical tools for studying fucosylated glycans

    Wu, P.

    National Institutes of Health

    9/15/10 → 7/31/20

    Project: Research project

  • Orally available transition state inhibitors for triple negative breast cancer

    Isaacman, S., Schramm, V. L., Rose, S. A. & Rose, S. A.

    1/1/14 → 6/30/16

    Project: Research project

  • CELLULAR/MOLECULAR BASIS OF DEVELOPMENT: RESEARCH CENTER

    Callender, R., Goldberg, A., Krag, S., Roulhac, E., Lanier, R., Meshnick, S., Kappner, A., Harleston, B., Moses, Y., Roman, S. A., Williams, G., Pezzano, M., Staiano-Coico, L., Spatz, L., Hubbard, K., Govind, S., Simms, S., Russell, C., Coico, R., Tasayco, M., McBeth, D., Simmons, G., Meir, L., Balogh-Nair, V., Cosloy, S., Hoskins, S., Moore, C., Schulz, H., Boto, W., Venkatesh, T., Calhoun, D., Steinberg, M., Gunner, M., Wallman, J., Guyden, J., Buffenstein, R., Pezzano, M., Roman, S. A., Hubbard, K., Govind, S., Simms, S., Russell, C., Coico, R., Tasayco, M., McBeth, D., Simmons, G., Meir, L., Balogh-Nair, V., Cosloy, S., Hoskins, S., Moore, C., Schulz, H., Boto, W., Venkatesh, T., Calhoun, D., Steinberg, M., Gunner, M., Wallman, J., Guyden, J., Buffenstein, R. & Pezzano, M.

    3/1/85 → 7/31/14

    Project: Research project

  • RESONANCE RAMAN STUDIES OF RHODOPSIN &RELATED PIGMENTS

    Callender, R.

    12/31/89 → 6/30/97

    Project: Research project

  • In vivo imaging of X inactivation

    Greally, J. M. & Levy, M.

    National Institute on Drug Abuse

    9/15/10 → 5/31/16

    Project: Research project

  • Molecular and Cellular Mechanisms of the Lysosomal Storage Disease Cystinosis

    Cuervo, A. M. & Gavathiotis, E.

    8/9/17 → 5/31/22

    Project: Research project

  • Autophagy in aging: testing geroscience in Alzheimer's disease

    Cuervo, A. M., Bravo Cordero, J. J., Gavathiotis, E., Macian-Juan, F., Santambrogio, L. & Singh, R.

    National Institute on Aging

    2/15/09 → 3/31/24

    Project: Research project

  • Metabolomic Analysis of Redox control in Mycobacterium tuberculosis persisters

    Jacobs, W. R., Kurland, I. J. & Wu, P.

    National Institute of Allergy and Infectious Diseases

    6/1/10 → 1/31/13

    Project: Research project

  • RESEARCH TRAINING FOR BIO MEDICAL CAREERS

    Callender, R., Birke, R., Haines, T., Lee, J., Sloan, D., McKenna, O., Cosloy, S., Schulz, H., Russell, C., Wallman, J., Grossfield, J., Steiner, S., Lombardi, J., Akins, D., Rockwell, R., Green, M., Tietjen, J., Woodward, A. & Fishman, M.

    9/1/79 → 8/31/93

    Project: Research project

  • PERTUSSIS, DIPHTHERIA, CHOLERA TOXINS--INHIBITOR DESIGN

    Schramm, V. L.

    7/1/93 → 1/31/05

    Project: Research project

  • PI3K Beta regulation of tumor metastasis

    Bresnick, A. R.

    6/1/22 → 5/31/23

    Project: Research project

  • LASER DESORPTION MASS SPECTROMETRY OF LARGE SYNTHETIC PORPHYRIN ARRAYS

    Cowburn, D., Cerami, A., Lloyd, K., Prusiner, S., Gilman, A., Backlund, P., Breslow, J., Hugli, T., Kaiser, E., Buxbaum, J., Merrifield, B., Field, F., Lindsey, J. O. N., Nairn, A., Fenyo, J. U. N., Tang, H., Marian Orlowski, [. V., Shufang, N., Lipton, S., Hall, W., Makriyannis, A., Young, R., Cross, F. R., Jordan, W., Spiegel, A. M., Orlowski, M., Leonard, J., Wlodawer, A., Kufe, D. W., Wang, Z., Yoshiya, O., Dodd, J. O. N., O'Donnell, M., Upmacis, R., Padovan, J., Nakanishi, K., Ho, D., Grendell, J., Cardozo, C., Tjernberg, A., Speigel, A., Eriksson, J. A. N., Peterson, C., Yanagisawa, K., Miller, D. L., Lazarow, P., Shufang, N., Trester, M., Beyreuther, K., Gandy, S., Duff, K., Gotschlich, E. C., Cadene, M., Rout, M., Hajjar, K. A., Tischer, E. D., Spiegel, A. M., Nussenzweig, R., Orlowski, M., Greene, L., Leonard, J., Wlodawer, A., Kufe, D. W., Shufang, N., Lipton, S., Hall, W., Smith, A., Canfield, R., Lander, H., Lindsey, J. O. N., Miller, C., Bradley, C., Seibert, C., Degrasse, J., O'Donnell, M., Oelgeschlager, T., Kipper, J., Matunis, M. J., Dutzler, R., Gu, W. E. I., Campbell, E., Jiang, Y., Duff, K., Severinov, K., Kato, H., Zhang, J., McLachlin, D., Nogoceke, E., Zimniak, P., Trester, M., Kretzschmar, M., Demmers, J., Zhang, W., Shengkan Victor, J., Luo, Y. A. N., Lima, C., Cadene, M., Sehayek, E., Jin, M. I., Tackett, A. J., Wang, R., Gadsby, D., Vallee, R. B., Stoffel, M., De Lange, T., Kalkum, M., Chen, E. L. I., Makriyannis, A., Ravetch, J. V., Hajjar, K. A., Chua, N., Krutchinsky, A. N., Darst, S., Riggs, A., Christea, I., Rice, C. M., Kreek, M., Manning, J., Nairn, A. C., Muir, T., Tarakhovsky, A., Cross, F. R., Muesing, M. A., Padovan, J., Chang, E., Kim, Y., Darnell, J., Roeder, R., Greengard, P., Allis, C. D., Rout, M., Hingorani, M., Deshaies, R., Aitchison, J. D., Sakmar, T., Shenk, T., Funabiki, H., Weiss, E., Cross, G. A. M., Jacobs, E., Zhenyu, Y., Sali, A., Sekedat, M., Kraus, W., Stellar, H., Varmus, H., Woolford, J. L., Wang, Q., Andren, P., Glavy, J. S., Severinov, K., Fischetti, V. A., Jeruzalmi, D., Beavis, R. C., Eileen, W., Ueberheide, B., Engelberg-Kulka, H., Fenyo, D., Abreu, I., Varmus, H. E., Jordan, B., Steller, H., Logothetis, D. E., Bern, M. W., Goddard, N. L., Holford, M. N., Kapoor, T., Myung, S., Keeney, S., Stebbins, C. E., Malamud, D., Oakley, M. G., Steinman, R. M., Boeke, J., Wendel, H., Hudspeth, A. J., Molloy, K., Field, M., Gautier, J., Raleigh, D., Minakhin, L., Varmus, H., Neubert, T., Tomasz, A., Heintz, N., Blobel, G., Werner, M. H., MacKinnon, R., Giriat, I., Muller, M., Romanelli, A., Nussenzweig, M., MacKinnon, R., Blobel, G., Kappas, A., Bradshaw, R., Tang, H., Buku, A., Unson, C., Marchal, G., Goodman, S., Lin Yao-Zhong, L. I. N., Aebersold, R. H., Haley, J., Tam, J., Xioadong, W., Friedman, J., Kent, S., Birken, S., Severinov, K., Nussenzweig, R., Greene, L., Smith, A., Canfield, R., Lander, H., Kreek, M., Stuart, A., Cohen, S., Pochapsky, T. C., Merrifield, R., Manning, J., Adzuma, K., Wang, R., Gadsby, D., Darst, S., Lindsey, J., Burley, S., Mirza, U., Zhang, W., Zhao, Y., Darnell, J., Riggs, A., Roeder, R., Greengard, P., Kuriyan, J., Fenyo, D., Qin, J. U. N., Chait, B., Sechi, S., Tomasz, A., Lloyd, K., Kaiser, E., Lindsey, J. O. N., Nairn, A., Fenyo, J. U. N., Tang, H., Marian Orlowski, [. V., Cross, F. R., Spiegel, A. M., Kufe, D. W., Dodd, J. O. N., Werner, M. H., Eriksson, J. A. N., Miller, D. L., Gotschlich, E. C., Tischer, E. D., Spiegel, A. M., Kufe, D. W., Lindsey, J. O. N., Matunis, M. J., Gu, W. E. I., Luo, Y. A. N., Jin, M. I., Chen, E. L. I., Krutchinsky, A. N., Rice, C. M., Nairn, A. C., Cross, F. R., Aitchison, J. D., Woolford, J. L., Fischetti, V. A., Beavis, R. C., Varmus, H. E., Logothetis, D. E., Goddard, N. L., Holford, M. N., Oakley, M. G., Kappas, A., Bradshaw, R., Tang, H., Buku, A., Unson, C., Marchal, G., Goodman, S., Lin Yao-Zhong, L. I. N., Aebersold, R. H., Haley, J., Tam, J., Xioadong, W., Friedman, J., Kent, S., Birken, S., Severinov, K., Nussenzweig, R., Greene, L., Smith, A., Canfield, R., Lander, H., Kreek, M., Stuart, A., Cohen, S., Pochapsky, T. C., Merrifield, R., Manning, J., Adzuma, K., Wang, R., Gadsby, D., Darst, S., Lindsey, J., Burley, S., Mirza, U., Zhang, W., Zhao, Y., Darnell, J., Riggs, A., Roeder, R., Greengard, P., Kuriyan, J., Fenyo, D., Qin, J. U. N., Chait, B. & Sechi, S.

    1/1/01 → 2/29/08

    Project: Research project

  • Amplifying and Redirecting CMV-specific CD8 T cells to provide sustained control of HIV infection

    Goldstein, H. & Almo, S. C.

    6/3/22 → 5/31/23

    Project: Research project

  • Protein architecture and Energy Landscape of Enzymes

    Callender, R.

    National Institute of General Medical Sciences

    8/15/14 → 4/30/19

    Project: Research project

  • Targeting Clostridioides difficile with microbiome-sparing, resistant-proof anti-toxins

    Schramm, V. L.

    National Institute of Allergy and Infectious Diseases

    4/1/21 → 3/31/24

    Project: Research project

  • Mechanistic and functional analysis of the proteasome activator Blm10

    Schmidt, M.

    National Institute of General Medical Sciences

    5/1/09 → 2/28/14

    Project: Research project

  • Transcriptional Repression by Maf1 in Yeast

    Willis, I. M. & Rose, S. A.

    3/1/09 → 2/28/14

    Project: Research project

  • The Role of PI3Kbeta in Breast Cancer Metastasis

    Backer, J. M. & Bresnick, A. R.

    8/1/16 → 7/31/21

    Project: Research project

  • The Role of PI3Kbeta in Breast Cancer Metastasis

    Backer, J. M. & Bresnick, A. R.

    National Institute of General Medical Sciences

    8/1/16 → 7/31/21

    Project: Research project

  • The dynamic mechanism of nuclear transport visualized at the atomic scale

    Cowburn, D.

    3/1/16 → 7/31/21

    Project: Research project