[Warfarin effects diminishment by the Clostridium butyricum preparation after cardiac surgery; report of a case]

Takuya Maeda; Hiroyuki Tsukui; Nobuhiro Umehara; Shizuko Iwasa; Tadahisa Sugiura; Minako Hayakawa; Yayoi Kawano; Kenji Yamazaki

[Warfarin effects diminishment by the Clostridium butyricum preparation after cardiac surgery; report of a case]

Takuya Maeda, Hiroyuki Tsukui, Nobuhiro Umehara, Shizuko Iwasa, Tadahisa Sugiura, Minako Hayakawa, Yayoi Kawano, Kenji Yamazaki

Research output: Contribution to journal › Article › peer-review

Abstract

A 55-year-old gentleman diagnosed with severe aortic insufficiency and annuloaortic ectasia underwent modified Bentall procedure using mechanical valve. Anticoagulation therapy with warfarin was introduced after surgery, but sufficient anticoagulation effect was not achieved with a large amount of dosage. After discontinuing the use of the Clostridium butyricum preparation on postoperative day 29, sufficient anticoagulationt effect was obtained within several days. Clostridium butyricum might change the vitamin K production in the intestinal bacterial flora and attenuated the anticoagulation effect of warfarin.

Original language	English (US)
Pages (from-to)	505-507
Number of pages	3
Journal	Kyobu geka. The Japanese journal of thoracic surgery
Volume	67
Issue number	6
State	Published - Jun 1 2014
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "[Warfarin effects diminishment by the Clostridium butyricum preparation after cardiac surgery; report of a case]",

abstract = "A 55-year-old gentleman diagnosed with severe aortic insufficiency and annuloaortic ectasia underwent modified Bentall procedure using mechanical valve. Anticoagulation therapy with warfarin was introduced after surgery, but sufficient anticoagulation effect was not achieved with a large amount of dosage. After discontinuing the use of the Clostridium butyricum preparation on postoperative day 29, sufficient anticoagulationt effect was obtained within several days. Clostridium butyricum might change the vitamin K production in the intestinal bacterial flora and attenuated the anticoagulation effect of warfarin. ",

author = "Takuya Maeda and Hiroyuki Tsukui and Nobuhiro Umehara and Shizuko Iwasa and Tadahisa Sugiura and Minako Hayakawa and Yayoi Kawano and Kenji Yamazaki",

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T1 - [Warfarin effects diminishment by the Clostridium butyricum preparation after cardiac surgery; report of a case]

AU - Maeda, Takuya

AU - Tsukui, Hiroyuki

AU - Umehara, Nobuhiro

AU - Iwasa, Shizuko

AU - Sugiura, Tadahisa

AU - Hayakawa, Minako

AU - Kawano, Yayoi

AU - Yamazaki, Kenji

PY - 2014/6/1

Y1 - 2014/6/1

N2 - A 55-year-old gentleman diagnosed with severe aortic insufficiency and annuloaortic ectasia underwent modified Bentall procedure using mechanical valve. Anticoagulation therapy with warfarin was introduced after surgery, but sufficient anticoagulation effect was not achieved with a large amount of dosage. After discontinuing the use of the Clostridium butyricum preparation on postoperative day 29, sufficient anticoagulationt effect was obtained within several days. Clostridium butyricum might change the vitamin K production in the intestinal bacterial flora and attenuated the anticoagulation effect of warfarin.

AB - A 55-year-old gentleman diagnosed with severe aortic insufficiency and annuloaortic ectasia underwent modified Bentall procedure using mechanical valve. Anticoagulation therapy with warfarin was introduced after surgery, but sufficient anticoagulation effect was not achieved with a large amount of dosage. After discontinuing the use of the Clostridium butyricum preparation on postoperative day 29, sufficient anticoagulationt effect was obtained within several days. Clostridium butyricum might change the vitamin K production in the intestinal bacterial flora and attenuated the anticoagulation effect of warfarin.

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SN - 0021-5252

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JF - Kyobu geka. The Japanese journal of thoracic surgery

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ER -

[Warfarin effects diminishment by the Clostridium butyricum preparation after cardiac surgery; report of a case]

Abstract

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