Visual Evoked Potentials in Chiasmal Gliomas in Four Adults

Mark J. Kupersmith, Irwin M. Siegel, Ronald E. Carr, Joseph Ransohoff, Eugene Flamm, Eric Shakin

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Visual evoked potentials (VEPs) were recorded from four patients with surgically verified chiasmal gliomas. Despite good visual acuity, 6/12 (20/40) or better in each eye, these patients showed substantially reduced VEP amplitudes to a diffuse flash stimulus and hardly detectable responses to a highly textured checkerboard-pattern stimulus. The dissociation between evoked electrical activity and visual acuity is noteworthy; this differs from previously reported findings in patients with extrinsic compressing lesions of the chiasm or with lesions of demyelinating disease, which usually reduce VEP amplitude and increase conduction time in rough proportion to a loss of visual acuity.

Original languageEnglish (US)
Pages (from-to)362-365
Number of pages4
JournalArchives of Neurology
Issue number6
StatePublished - Jun 1981
Externally publishedYes

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


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