Viral Culture of HIV in Neonates

William D. Lyman, Ruy Soeiro, Arye Rubinstein, Anne Krivine, Pierre Lebon, Marianne Burgard, Marie Jeanne Mayaux, Christine Rouzioux

Research output: Contribution to journalLetterpeer-review


To the Editor: Burgard et al. (Oct. 22 issue)1 are to be congratulated on their use of very sensitive assays to detect infection with human immunodeficiency virus type 1 (HIV-1) in neonates and infants. However, in their Discussion the authors state that the frequency of transmission of this virus from infected women to their fetuses is not known and that there is an apparent absence of the viral genome in fetal tissues. The authors take this as evidence that vertical transmission occurs at birth and not prenatally. To support these conclusions, they cite three papers. However, other studies that do…

Original languageEnglish (US)
Pages (from-to)814-815
Number of pages2
JournalNew England Journal of Medicine
Issue number11
StatePublished - Mar 18 1993

ASJC Scopus subject areas

  • Medicine(all)


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