Ventricular perforation

Mei Chau, Alfonso Ielasi, Azeem Latib

Research output: Chapter in Book/Report/Conference proceedingChapter


The use of transcatheter aortic valve implantation (TAVI) continues to grow worldwide, with over 100 000 procedures performed between 2002 and 2013. Along with the significant clinical benefit demonstrated from transfemoral (TF) TAVI compared to surgical aortic valve replacement (SAVR) in high-to-moderate risk patients, recent clinical trials showed non-inferiority of TF-TAVI with self-expandable valves and superiority with balloon-expandable valves, even in low risk patients. This chapter presents the current knowledge on diagnosis, management and prevention of left-and right-sided ventricular perforation (VP) complicating TF-TAVI. The clinical presentation of VP can be highly variable, ranging from rapid-onset cardiac tamponade to a "silent" LV pseudoaneurysm. Some techniques for LV perforation repairs are extrapolated from free wall ruptures secondary to acute myocardial infarctions (noting the difference of surrounding viable myocardium) while other techniques are extrapolated from repair of cardiac traumatic injuries.

Original languageEnglish (US)
Title of host publicationAortic Valve Transcatheter Intervention
Subtitle of host publicationComplications and Solutions
Number of pages10
ISBN (Electronic)9781119720621
ISBN (Print)9781119720591
StatePublished - Mar 19 2021
Externally publishedYes


  • Acute myocardial infarctions
  • Cardiac traumatic injuries
  • Clinical presentation
  • Left-sided ventricular perforation
  • Right-sided ventricular perforation
  • Surgical aortic valve replacement
  • Transcatheter aortic valve implantation

ASJC Scopus subject areas

  • Medicine(all)


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