Type 2 Diabetes Mellitus and Pancreatic Cancer

John C. McAuliffe, John D. Christein

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


Tumorigenesis of pancreatic cancer (PC) and the pathophysiology of type 2 diabetes mellitus (DM2) are emerging as intertwined pathways. As the operative morbidity and mortality of pancreatectomy has improved, incidence has increased and survival has remained mostly unchanged. The diagnosis of DM2 suggests pancreatic dysfunction and possible early carcinogenesis. DM2 is a significant comorbidity predicting worse outcomes in patients undergoing pancreatic resection as part of the treatment of PC. This article examines this phenomena and suggests possible approaches to screening and diagnosis.

Original languageEnglish (US)
Pages (from-to)619-627
Number of pages9
JournalSurgical Clinics of North America
Issue number3
StatePublished - Jun 2013
Externally publishedYes


  • Pancreatectomy
  • Pancreatic cancer
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Type 2 Diabetes Mellitus and Pancreatic Cancer'. Together they form a unique fingerprint.

Cite this