Twin pregnancy with discordancy for Down's syndrome

Majida N. Jassani, Irwin R. Merkatz, James N. Brennan, Neil M. Macintyre

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


A twin pregnancy is described in which discordancy for Down's syndrome was diagnosed prenatally by karyotyping amniotic fluid cell cultures from each of the 2 sacs. The advantages of ultrasonography prior to genetic amniocentesis are discussed from this perspective. The observation that parents may deal in various ways with the reality of this prenatal dilemma demands an open-minded approach from obstetricians and genetic counselors.

Original languageEnglish (US)
Pages (from-to)45S-46S
JournalObstetrics and gynecology
Issue number3
StatePublished - Mar 1980
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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