Treated Rosai-Dorfman disease: An unusual cause of biliary obstruction

Zina J. Ricci, Alla M. Rozenblit, Morris Edelman, Daniel Berkowitz, Ronald Kaleya

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


We report a case of a 50-year old woman with Rosai-Dorfman disease who presented five years prior to admission with vague abdominal pain secondary to bulky peripancreatic lymphadenopathy mimicking lymphoma on CT scan. She was treated successfully with chemotherapy. Five years later she presented with right upper quadrant pain, fevers and progressive jaundice. Imaging demonstrated intrahepatic and extrahepatic biliary ductal dilatation with an appearance of primary sclerosing cholangitis, cholelithiasis, and recurrent small upper abdominal lymph nodes. Abdominal MRI revealed discrete abnormal peripancreatic signal consistent with fibrosis which we believe reflected healed Rosai-Dorfman disease leading to intractable biliary obstruction. There are no cases to our knowledge of biliary obstruction related to this uncommon disease.

Original languageEnglish (US)
Pages (from-to)26-34
Number of pages9
JournalPractical Gastroenterology
Issue number12
StatePublished - Dec 1 2002

ASJC Scopus subject areas

  • Gastroenterology


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