Transoral robotic surgery in oropharyngeal carcinoma

Samuel N. Helman, Thomas Schwedhelm, Sameep Kadakia, Yanhua Wang, Bradley A. Schiff, Richard V. Smith

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Context.-The incidence of oropharyngeal squamous cell carcinoma has increased during the past decade and is related primarily to the human papillomavirus. This change in etiology, from tobacco and alcohol to human papillomavirus, has resulted in improved survival for the disease. In the United States, open resection had largely been replaced by concurrent chemotherapy and/or radiotherapy by the early 2000s. The advent of transoral surgery has led to an increase in surgery as the primary treatment for both early- and advanced-stage oropharyngeal squamous cell carcinoma because it has potential advantages over open surgery and nonsurgical modalities. Objective.-To provide an overview of transoral robotic surgery for oropharyngeal squamous cell carcinoma and contrast it with other surgical and nonsurgical modalities. Data Sources.-Articles from 2000 to 2014 were accessioned on PubMed and reviewed for utility by the primary authors. Conclusions.-Transoral surgery has become more commonly used as a minimally invasive approach to treat oropharyngeal tumors. Other strategies, including radiation, chemotherapy with radiation, and open surgery, are still important treatment approaches. The treatment options for an individual patient rely on multiple factors, including the tumor location and size, features of the tumor, and patient comorbidities. The continued study of these techniques is important to match the patient with the most appropriate treatment.

Original languageEnglish (US)
Pages (from-to)1389-1397
Number of pages9
JournalArchives of Pathology and Laboratory Medicine
Issue number11
StatePublished - Nov 2015

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology


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