Translocation of oncogene c-sis from chromosome 22 to chromosome 17 in a human myelogenous leukemia cell line

Pasquale Tripputi; Linda A. Cannizzaro; James Kuo; Daniela Biassoni; Gianmarco Corneo

doi:10.1159/000205977

Translocation of oncogene c-sis from chromosome 22 to chromosome 17 in a human myelogenous leukemia cell line

Pasquale Tripputi, Linda A. Cannizzaro, James Kuo, Daniela Biassoni, Gianmarco Corneo

Pathology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

By combining somatic cell genetics, in situ hybridization and Southern hybridization, we found that the c-sis oncogene in the human myelogenous leukemia cell line ML₃is translocated from the long arm (q 11 →qter) of chromosome 22 to the long arm (mid-portion or q21 region) of chromosome 17. This translocation does not result in rearrangement of the c-sis oncogene.

Original language	English (US)
Pages (from-to)	135-139
Number of pages	5
Journal	Acta Haematologica
Volume	77
Issue number	3
DOIs	https://doi.org/10.1159/000205977
State	Published - 1987

Keywords

Chromosomal translocation
Hybridization
In situ
Somatic cell hybrids

ASJC Scopus subject areas

Hematology

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10.1159/000205977

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title = "Translocation of oncogene c-sis from chromosome 22 to chromosome 17 in a human myelogenous leukemia cell line",

abstract = "By combining somatic cell genetics, in situ hybridization and Southern hybridization, we found that the c-sis oncogene in the human myelogenous leukemia cell line ML3is translocated from the long arm (q 11 →qter) of chromosome 22 to the long arm (mid-portion or q21 region) of chromosome 17. This translocation does not result in rearrangement of the c-sis oncogene.",

keywords = "Chromosomal translocation, Hybridization, In situ, Somatic cell hybrids",

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year = "1987",

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T1 - Translocation of oncogene c-sis from chromosome 22 to chromosome 17 in a human myelogenous leukemia cell line

AU - Tripputi, Pasquale

AU - Cannizzaro, Linda A.

AU - Kuo, James

AU - Biassoni, Daniela

AU - Corneo, Gianmarco

PY - 1987

Y1 - 1987

N2 - By combining somatic cell genetics, in situ hybridization and Southern hybridization, we found that the c-sis oncogene in the human myelogenous leukemia cell line ML3is translocated from the long arm (q 11 →qter) of chromosome 22 to the long arm (mid-portion or q21 region) of chromosome 17. This translocation does not result in rearrangement of the c-sis oncogene.

AB - By combining somatic cell genetics, in situ hybridization and Southern hybridization, we found that the c-sis oncogene in the human myelogenous leukemia cell line ML3is translocated from the long arm (q 11 →qter) of chromosome 22 to the long arm (mid-portion or q21 region) of chromosome 17. This translocation does not result in rearrangement of the c-sis oncogene.

KW - Chromosomal translocation

KW - Hybridization

KW - In situ

KW - Somatic cell hybrids

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JF - Acta Haematologica

IS - 3

ER -

Translocation of oncogene c-sis from chromosome 22 to chromosome 17 in a human myelogenous leukemia cell line

Abstract

Keywords

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