Transcatheter mitral valve replacement: Current evidence and concepts

Ozan M. Demir, Mhairi Bolland, Jonathan Curio, Lars Søndergaard, Josep Rodés-Cabau, Simon Redwood, Bernard Prendergast, Antonio Colombo, Mei Chau, Azeem Latib

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Over the past decade, several transcatheter devices have been developed to address the treatment of severe mitral regurgitation (MR) in patients at high surgical risk, mainly aimed at repairing the native mitral valve (MV). MV repair devices have recently been shown to have high efficacy and safety. However, to replicate promising trial results, specific anatomical and pathophysiological criteria have to be met and operators need a high level of experience. As yet, the longer-term durability of transcatheter MV repair remains unknown. Transcatheter MV replacement (TMVR) might be a treatment option able to target various anatomies, reliably abolish MR, and foster ease of use with a standardised implantation protocol. This review presents upcoming TMVR devices and available data and discusses how TMVR might further advance the field of transcatheter treatment of MR.

Original languageEnglish (US)
JournalInterventional Cardiology: Reviews, Research, Resources
StatePublished - 2021


  • Heart failure
  • Mitral regurgitation
  • Percutaneous mitral valve replacement
  • Transcatheter mitral valve repair
  • Transcatheter mitral valve replacement

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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