Toward a Uniform Ablation Protocol for Paroxysmal, Persistent, and Permanent Atrial Fibrillation

Domenico Giovanni Della Rocca, Carlo Lavalle, Carola Gianni, Marco Valerio Mariani, Sanghamitra Mohanty, Chintan Trivedi, Ugur Canpolat, Bryan MacDonald, Huseyin Ayhan, Agostino Piro, Mohamed Bassiouny, Amin Al-Ahmad, John David Burkhardt, Joseph G. Gallinghouse, Rodney P. Horton, Javier Sanchez, Nicola Tarantino, Luigi Di Biase, Andrea Natale

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Atrial fibrillation catheter ablation has emerged as the most effective strategy to restore and maintain sinus rhythm. The cornerstone of atrial fibrillation ablation is elimination of triggers from the pulmonary veins by pulmonary vein isolation. Nevertheless, some patients may experience atrial tachyarrhythmia recurrences even with permanent pulmonary vein antral isolation. Whether and in which patients pulmonary vein antral isolation should be considered as the only ablation strategy remains a matter of debate. This review aims to summarize the rationale and effectiveness of different ablation approaches and identify key points for a uniform atrial fibrillation ablation strategy.

Original languageEnglish (US)
Pages (from-to)731-738
Number of pages8
JournalCardiac Electrophysiology Clinics
Issue number4
StatePublished - Dec 2019


  • Anticoagulation
  • Atrial fibrillation
  • Catheter ablation
  • Outcome
  • Stroke
  • Substrate
  • Trigger

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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