Tools for comparative protein structure modeling and analysis

Narayanan Eswar, Bino John, Nebojsa Mirkovic, Andras Fiser, Valentin A. Ilyin, Ursula Pieper, Ashley C. Stuart, Marc A. Marti-Renom, M. S. Madhusudhan, Bozidar Yerkovich, Andrej Sali

Research output: Contribution to journalArticlepeer-review

400 Scopus citations


The following resources for comparative protein structure modeling and analysis are described ( MODELLER, a program for comparative modeling by satisfaction of spatial restraints; MODWEB, a web server for automated comparative modeling that relies on PSI-BLAST, IMPALA and MODELLER; MODLOOP, a web server for automated loop modeling that relies on MODELLER; MOULDER, a CPU intensive protocol of MODWEB for building comparative models based on distant known structures; MODBASE, a comprehensive database of annotated comparative models for all sequences detectably related to a known structure; MODVIEW, a Netscape plugin for Linux that integrates viewing of multiple sequences and structures; and SNPWEB, a web server for structure-based prediction of the functional impact of a single amino acid substitution.

Original languageEnglish (US)
Pages (from-to)3375-3380
Number of pages6
JournalNucleic acids research
Issue number13
StatePublished - Jul 1 2003

ASJC Scopus subject areas

  • Genetics


Dive into the research topics of 'Tools for comparative protein structure modeling and analysis'. Together they form a unique fingerprint.

Cite this