The use of mitomycin C in pediatric airway surgery: Does it work?

Mona Gangar; John P. Bent

doi:10.1097/MOO.0000000000000110

The use of mitomycin C in pediatric airway surgery: Does it work?

Mona Gangar, John P. Bent

Otorhinolaryngology - Head & Neck Surgery

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

Purpose of review: To describe the efficacy of mitomycin C in combating airway stenosis. Recent findings: Recent publications discussing mitomycin C utility have not altered the mixed results previously established by prospective trials. Summary: Mitomycin C has been used for the past 16 years to inhibit pediatric airway fibroblast proliferation. Its benefit remains more hypothetical than proven and its future role remains uncertain.

Original language	English (US)
Pages (from-to)	521-524
Number of pages	4
Journal	Current Opinion in Otolaryngology and Head and Neck Surgery
Volume	22
Issue number	6
DOIs	https://doi.org/10.1097/MOO.0000000000000110
State	Published - 2014

Keywords

Choanal atresia
Laryngotracheal reconstruction
Mitomycin C

ASJC Scopus subject areas

Surgery
Otorhinolaryngology

Access to Document

10.1097/MOO.0000000000000110

Cite this

@article{8742d3ea54f04d588848c6240a42c13b,

title = "The use of mitomycin C in pediatric airway surgery: Does it work?",

abstract = "Purpose of review: To describe the efficacy of mitomycin C in combating airway stenosis. Recent findings: Recent publications discussing mitomycin C utility have not altered the mixed results previously established by prospective trials. Summary: Mitomycin C has been used for the past 16 years to inhibit pediatric airway fibroblast proliferation. Its benefit remains more hypothetical than proven and its future role remains uncertain.",

keywords = "Choanal atresia, Laryngotracheal reconstruction, Mitomycin C",

author = "Mona Gangar and Bent, {John P.}",

note = "Publisher Copyright: {\textcopyright} 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins.",

year = "2014",

doi = "10.1097/MOO.0000000000000110",

language = "English (US)",

volume = "22",

pages = "521--524",

journal = "Current Opinion in Otolaryngology and Head and Neck Surgery",

issn = "1068-9508",

publisher = "Lippincott Williams and Wilkins",

number = "6",

}

TY - JOUR

T1 - The use of mitomycin C in pediatric airway surgery

T2 - Does it work?

AU - Gangar, Mona

AU - Bent, John P.

PY - 2014

Y1 - 2014

N2 - Purpose of review: To describe the efficacy of mitomycin C in combating airway stenosis. Recent findings: Recent publications discussing mitomycin C utility have not altered the mixed results previously established by prospective trials. Summary: Mitomycin C has been used for the past 16 years to inhibit pediatric airway fibroblast proliferation. Its benefit remains more hypothetical than proven and its future role remains uncertain.

AB - Purpose of review: To describe the efficacy of mitomycin C in combating airway stenosis. Recent findings: Recent publications discussing mitomycin C utility have not altered the mixed results previously established by prospective trials. Summary: Mitomycin C has been used for the past 16 years to inhibit pediatric airway fibroblast proliferation. Its benefit remains more hypothetical than proven and its future role remains uncertain.

KW - Choanal atresia

KW - Laryngotracheal reconstruction

KW - Mitomycin C

UR - http://www.scopus.com/inward/record.url?scp=84927695716&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84927695716&partnerID=8YFLogxK

U2 - 10.1097/MOO.0000000000000110

DO - 10.1097/MOO.0000000000000110

M3 - Review article

C2 - 25254407

AN - SCOPUS:84927695716

SN - 1068-9508

VL - 22

SP - 521

EP - 524

JO - Current Opinion in Otolaryngology and Head and Neck Surgery

JF - Current Opinion in Otolaryngology and Head and Neck Surgery

IS - 6

ER -

The use of mitomycin C in pediatric airway surgery: Does it work?

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this