TY - JOUR
T1 - The role of immunotherapy in in vitro fertilization
T2 - a guideline
AU - Practice Committee of the American Society for Reproductive Medicine, ASRM@asrm.org, American Society for Reproductive Medicine, Birmingham, Alabama, USA
AU - Penzias, Alan
AU - Bendikson, Kristin
AU - Butts, Samantha
AU - Coutifaris, Christos
AU - Falcone, Tommaso
AU - Gitlin, Susan
AU - Gracia, Clarisa
AU - Hansen, Karl
AU - Jindal, Sangita
AU - Mersereau, Jennifer
AU - Odem, Randall
AU - Rebar, Robert
AU - Reindollar, Richard
AU - Rosen, Mitchell
AU - Sandlow, Jay
AU - Schlegel, Peter
AU - Stovall, Dale
AU - Vernon, Michael
N1 - Publisher Copyright:
© 2018 American Society for Reproductive Medicine
PY - 2018/8
Y1 - 2018/8
N2 - Adjuvant immunotherapy treatments in in vitro fertilization (IVF) aim to improve the outcome of assisted reproductive technology (ART) in both the general ART population as well as subgroups such as patients with recurrent miscarriage or implantation failure. The purpose of this guideline is to evaluate the role of immunomodulating therapy in ART. Unfortunately, many of the evaluated therapies lack robust evidence from well-designed adequately powered randomized controlled trials to support their use. Immunotherapies reviewed in the present document are either not associated with improved live-birth outcome in IVF or have been insufficiently studied to make definitive recommendations.
AB - Adjuvant immunotherapy treatments in in vitro fertilization (IVF) aim to improve the outcome of assisted reproductive technology (ART) in both the general ART population as well as subgroups such as patients with recurrent miscarriage or implantation failure. The purpose of this guideline is to evaluate the role of immunomodulating therapy in ART. Unfortunately, many of the evaluated therapies lack robust evidence from well-designed adequately powered randomized controlled trials to support their use. Immunotherapies reviewed in the present document are either not associated with improved live-birth outcome in IVF or have been insufficiently studied to make definitive recommendations.
UR - http://www.scopus.com/inward/record.url?scp=85051120646&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85051120646&partnerID=8YFLogxK
U2 - 10.1016/j.fertnstert.2018.05.009
DO - 10.1016/j.fertnstert.2018.05.009
M3 - Article
C2 - 30098685
AN - SCOPUS:85051120646
SN - 0015-0282
VL - 110
SP - 387
EP - 400
JO - Fertility and sterility
JF - Fertility and sterility
IS - 3
ER -