TY - JOUR
T1 - The Role of Cannabis Use in Suicidal Ideation Among Patients With Opioid Use Disorder
AU - Naji, Leen
AU - Rosic, Tea
AU - Sanger, Nitika
AU - Dennis, Brittany
AU - Worster, Andrew
AU - Paul, James
AU - Thabane, Lehana
AU - Samaan, Zainab
N1 - Funding Information:
Dr. Samaan is supported by grants from CIHR Awards #156306 and #155404.
Publisher Copyright:
© 2022 Published by Wolters Kluwer on behalf of ASCRS and ESCRS Published by Wolters Kluwer Health, Inc.
PY - 2021/9/1
Y1 - 2021/9/1
N2 - Objectives:Cannabis use is associated with suicide risk in the general population; however, it is unknown if this association is also present in patients with opioid use disorder (OUD). The purpose of this study is to investigate the association between cannabis use and suicidal ideation in patients with OUD.Methods:We conducted a multivariable logistic regression analysis to assess the association between cannabis use and suicidal ideation, amongst a large cohort of patients with OUD. Current cannabis use and suicidal ideation over the past 30 days were obtained by self-report.Results:Cross-sectional data from 2335 participants with OUD were included in the analysis, of whom 51% report current cannabis use. We found a positive association between cannabis use and suicidal ideation (OR = 1.41, 95% CI 1.11, 1.80, P = 0.005). We found that men (OR = 1.84, 95% CI 1.44, 2.35, P < 0.001), younger individuals (OR = 1.02, 95% CI 1.01, 1.03), P = 0.004), and that those with more symptoms of anxiety or depression (OR = 1.16, 95% CI 1.15, 1.18, P < 0.001) were more likely to report suicidal ideation.Conclusions:Cannabis use is associated with a heightened propensity for suicidal ideation amongst patients with OUD, who are already a high-risk population. Further research into the potential harms of cannabis use in this population is required given the prevalence of its use and potential benefits in mitigating opioid withdrawal.
AB - Objectives:Cannabis use is associated with suicide risk in the general population; however, it is unknown if this association is also present in patients with opioid use disorder (OUD). The purpose of this study is to investigate the association between cannabis use and suicidal ideation in patients with OUD.Methods:We conducted a multivariable logistic regression analysis to assess the association between cannabis use and suicidal ideation, amongst a large cohort of patients with OUD. Current cannabis use and suicidal ideation over the past 30 days were obtained by self-report.Results:Cross-sectional data from 2335 participants with OUD were included in the analysis, of whom 51% report current cannabis use. We found a positive association between cannabis use and suicidal ideation (OR = 1.41, 95% CI 1.11, 1.80, P = 0.005). We found that men (OR = 1.84, 95% CI 1.44, 2.35, P < 0.001), younger individuals (OR = 1.02, 95% CI 1.01, 1.03), P = 0.004), and that those with more symptoms of anxiety or depression (OR = 1.16, 95% CI 1.15, 1.18, P < 0.001) were more likely to report suicidal ideation.Conclusions:Cannabis use is associated with a heightened propensity for suicidal ideation amongst patients with OUD, who are already a high-risk population. Further research into the potential harms of cannabis use in this population is required given the prevalence of its use and potential benefits in mitigating opioid withdrawal.
KW - cannabis
KW - opioid use disorder
KW - suicide
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UR - http://www.scopus.com/inward/citedby.url?scp=85118096336&partnerID=8YFLogxK
U2 - 10.1097/ADM.0000000000000781
DO - 10.1097/ADM.0000000000000781
M3 - Article
C2 - 33337662
AN - SCOPUS:85118096336
SN - 1932-0620
VL - 15
SP - 370
EP - 375
JO - Journal of addiction medicine
JF - Journal of addiction medicine
IS - 5
ER -
