TY - JOUR
T1 - The Relationship Between Pediatric Attention-Deficit/Hyperactivity Disorder Symptoms and Asthma Management
AU - Silverstein, Gabriella D.
AU - Arcoleo, Kimberly
AU - Rastogi, Deepa
AU - Serebrisky, Denise
AU - Warman, Karen
AU - Feldman, Jonathan M.
N1 - Funding Information:
This work was supported by the National Institutes of Health ( R01HL128260 to JMF) and ( CTSA 5UL1TR002556 ) as a part of NCT02702687 ( https://clinicaltrials.gov/ct2/show/NCT02702687 ). The study sponsor had no involvement in the current study design; collection, analysis and interpretation of data; writing of the report; or the decision to submit the article for publication. Everyone who has contributed significantly to this work has been listed as a manuscript author. Gabriella Silverstein wrote the first draft of the manuscript. No authors were provided with any honorariums, grants, or other forms of payment to produce this manuscript. These findings have previously been presented as a poster presentation at the 2022 Annual Meeting of the American Psychosomatic Society.
Funding Information:
This work was supported by the National Institutes of Health (R01HL128260 to JMF) and (CTSA 5UL1TR002556) as a part of NCT02702687 (https://clinicaltrials.gov/ct2/show/NCT02702687). The study sponsor had no involvement in the current study design; collection, analysis and interpretation of data; writing of the report; or the decision to submit the article for publication. Everyone who has contributed significantly to this work has been listed as a manuscript author. Gabriella Silverstein wrote the first draft of the manuscript. No authors were provided with any honorariums, grants, or other forms of payment to produce this manuscript. These findings have previously been presented as a poster presentation at the 2022 Annual Meeting of the American Psychosomatic Society.
Publisher Copyright:
© 2023 Society for Adolescent Health and Medicine
PY - 2023
Y1 - 2023
N2 - Purpose: Children with comorbid Attention-Deficit/Hyperactivity Disorder (ADHD) and asthma are at an increased risk for adverse health outcomes and reduced quality of life. The objective of these analyses was to examine if self-reported ADHD symptoms in children with asthma are associated with asthma control, asthma controller medication adherence, quick relief medication use, pulmonary function, and acute healthcare utilization. Methods: We analyzed data from a larger study testing a behavioral intervention for Black and Latinx children with asthma aged 10–17 years and their caregivers. Participants completed the Conners-3AI self-report assessment for ADHD symptoms. Asthma medication usage data were collected for 3 weeks following baseline via electronic devices fitted to participants' asthma medications. Other outcome measures included the Asthma Control Test, self-reported healthcare utilization, and pulmonary function measured by spirometry testing. Results: The study sample consisted of 302 pediatric participants with an average age of 12.8 years. Increased ADHD symptoms were directly associated with reduced adherence to controller medications, but no evidence of mediation was observed. Direct effects of ADHD symptoms on quick-relief medication use, health care utilization, asthma control, or pulmonary function were not observed. However, the effect of ADHD symptoms on emergency room visits was mediated by controller medication adherence. Discussion: ADHD symptoms were associated with significantly reduced asthma controller medication adherence and indirectly with emergency room visits. There are significant potential clinical implications to these findings, including the need for the development of interventions for pediatric asthma patients with ADHD.
AB - Purpose: Children with comorbid Attention-Deficit/Hyperactivity Disorder (ADHD) and asthma are at an increased risk for adverse health outcomes and reduced quality of life. The objective of these analyses was to examine if self-reported ADHD symptoms in children with asthma are associated with asthma control, asthma controller medication adherence, quick relief medication use, pulmonary function, and acute healthcare utilization. Methods: We analyzed data from a larger study testing a behavioral intervention for Black and Latinx children with asthma aged 10–17 years and their caregivers. Participants completed the Conners-3AI self-report assessment for ADHD symptoms. Asthma medication usage data were collected for 3 weeks following baseline via electronic devices fitted to participants' asthma medications. Other outcome measures included the Asthma Control Test, self-reported healthcare utilization, and pulmonary function measured by spirometry testing. Results: The study sample consisted of 302 pediatric participants with an average age of 12.8 years. Increased ADHD symptoms were directly associated with reduced adherence to controller medications, but no evidence of mediation was observed. Direct effects of ADHD symptoms on quick-relief medication use, health care utilization, asthma control, or pulmonary function were not observed. However, the effect of ADHD symptoms on emergency room visits was mediated by controller medication adherence. Discussion: ADHD symptoms were associated with significantly reduced asthma controller medication adherence and indirectly with emergency room visits. There are significant potential clinical implications to these findings, including the need for the development of interventions for pediatric asthma patients with ADHD.
KW - ADHD
KW - Asthma
KW - Medication adherence
KW - Minority groups
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U2 - 10.1016/j.jadohealth.2023.02.028
DO - 10.1016/j.jadohealth.2023.02.028
M3 - Article
C2 - 37074236
AN - SCOPUS:85153094898
SN - 1054-139X
JO - Journal of Adolescent Health
JF - Journal of Adolescent Health
ER -
