The Puzzle of Passive Immunity

Research output: Contribution to journalLetterpeer-review


To the Editor: “Passive immunity” is defined as immunologic protection by factors not produced by the organism itself. In general, the term refers to the receipt of immunoglobulin, although such processes as neutrophil transfusions, for example, could also be said to confer passive immunity. The salient feature of passive immunity is that it lasts only as long as the administered factor remains in sufficient quantity in the recipient. The puzzle arises when Jerne's network hypothesis is considered.1 Burdette and Schwartz's review of idiotypic networks2 outlined what is currently known about idiotypic interactions. According to their description, exogenous antibody conferring passive.

Original languageEnglish (US)
Pages (from-to)1067
Number of pages1
JournalNew England Journal of Medicine
Issue number16
StatePublished - Apr 21 1988
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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