The pharmacotherapy of moral or religious scrupulosity

B. A. Fallon, M. R. Liebowitz, E. Hollander, F. R. Schneier, R. B. Campeas, J. Fairbanks, L. A. Papp, J. A. Hatterer, D. Sandberg

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Moral or religious scrupulosity is a disabling condition which is sometimes seen in patients with obsessive compulsive disorder (OCD). The authors describe 10 patients with moral or religious scrupulosity who were treated with fluoxetine or clomipramine. Seven of the 10 patients completed open treatment of at least 8 weeks without requiring adjunctive medication; 5 of those 7 patients were rated as much improved. Among the 3 patients who required adjunctive medication, 1 was rated as much improved. Of the 4 nonresponders at 3 months, 2 responded after longer treatment trials. These results suggest that extreme moral or religious concerns and behaviors might be a form of OCD and that the scrupulosity can be effectively treated with serotonin reuptake blockers.

Original languageEnglish (US)
Pages (from-to)517-521
Number of pages5
JournalJournal of Clinical Psychiatry
Issue number12
StatePublished - Dec 1 1990
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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