The pathogenesis of fatal outcome in murine pulmonary aspergillosis depends on the neutrophil depletion strategy

Agriculture & Biology

• aspergillosis 97%
• neutrophils 65%
• pathogenesis 63%
• lungs 54%
• mice 40%
• neutropenia 23%
• inflammation 21%
• monoclonal antibodies 20%
• inoculum 19%
• death 17%
• infection 12%
• immunocompromised population 11%
• cyclophosphamide 9%
• immunosuppression 9%
• Aspergillus fumigatus 8%
• aerosols 8%
• histopathology 8%
• granulocytes 8%
• human diseases 8%
• animal models 6%
• therapeutics 5%
• methodology 2%

Medicine & Life Sciences

• Pulmonary Aspergillosis 100%
• Fatal Outcome 81%
• Neutrophils 54%
• Monoclonal Antibodies 21%
• Neutropenia 19%
• Inbred C57BL Mouse 18%
• Infections 14%
• Tissue Survival 12%
• Aspergillus fumigatus 12%
• Aspergillosis 11%
• Aerosols 10%
• Immunocompromised Host 10%
• Granulocytes 9%
• Cyclophosphamide 9%
• Immunosuppression 8%
• Pneumonia 8%
• Animal Models 7%
• Inflammation 5%
• Lung 5%
• Mortality 4%
• Therapeutics 1%