The overlap between personality disorders and major depressive disorder (MDD)

Amy Farabaugh, David Mischoulon, Maurizio Fava, Wendy Guyker, Jonathan Alpert

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations

Abstract

Background. Research studies have focused attention on the importance of the comorbidity of personality disorders and depression. Methods. The present review examines seven potential explanations for the overlap to clarify the nature of the relationship, if any, between depression and personality disorder diagnoses. Results. There may be many explanations for the potential overlap of personality disorders (PD) and major depressive disorder (MDD). For example, the distinction between states and traits may not be as clear and definitive as suggested in the DSM-IV. In some cases, depression may influence personality pathology, and may even lead to personality disorders. In other cases, personality disorders may lead to MDD. Conclusion. Further research may clarify the nature of the relationship, if any, between depression and personality disorder diagnoses, as well as the relationship between comorbidity and treatment response.

Original languageEnglish (US)
Pages (from-to)217-224
Number of pages8
JournalAnnals of Clinical Psychiatry
Volume16
Issue number4
DOIs
StatePublished - Oct 2004
Externally publishedYes

Keywords

  • Comorbidity
  • Depression
  • Personality pathology

ASJC Scopus subject areas

  • Psychiatry and Mental health

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