The neuropharmacology of attention-deficit hyperactivity disorder

A. J. Zametkin, B. G. Borcherding

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


Attention-deficit hyperactivity disorder, as described in the American Psychiatric Association's diagnostic manual DSM III-R (1), is a broadly defined syndrome of cognitive and behavioral problems that were originally found in children, but that have been increasingly identified in adults who had similar complaints in childhood (2). This paper briefly reviews the definition and treatment of this syndrome in children, evidence for specific neurochemical abnormalities, and effects of stimulants on neurochemistry. Finally, problems of diagnosis and treatment in adults are discussed.

Original languageEnglish (US)
Pages (from-to)447-451
Number of pages5
JournalAnnual Review of Medicine
StatePublished - 1989
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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