The Ins and Outs of MHC Class II Proteins in Dendritic Cells

Laura Santambrogio; Jack L. Strominger

doi:10.1016/j.immuni.2006.11.007

The Ins and Outs of MHC Class II Proteins in Dendritic Cells

Laura Santambrogio, Jack L. Strominger

Research output: Contribution to journal › Short survey › peer-review

15 Scopus citations

Abstract

One more mechanism for regulating surface expression of MHC class II proteins in dendritic cells (an important process that regulates both tolerance and immunity) has been uncovered, polyubiquitination of Lys225 in the intracytoplasmic region and subsequent endocytosis and proteolysis (Omura-Hoshino et al., 2006; van Neil et al., 2006; Shin et al., 2006).

Original language	English (US)
Pages (from-to)	857-859
Number of pages	3
Journal	Immunity
Volume	25
Issue number	6
DOIs	https://doi.org/10.1016/j.immuni.2006.11.007
State	Published - Dec 2006
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.immuni.2006.11.007

Cite this

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title = "The Ins and Outs of MHC Class II Proteins in Dendritic Cells",

abstract = "One more mechanism for regulating surface expression of MHC class II proteins in dendritic cells (an important process that regulates both tolerance and immunity) has been uncovered, polyubiquitination of Lys225 in the intracytoplasmic region and subsequent endocytosis and proteolysis (Omura-Hoshino et al., 2006; van Neil et al., 2006; Shin et al., 2006).",

author = "Laura Santambrogio and Strominger, {Jack L.}",

year = "2006",

month = dec,

doi = "10.1016/j.immuni.2006.11.007",

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volume = "25",

pages = "857--859",

journal = "Immunity",

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AU - Santambrogio, Laura

AU - Strominger, Jack L.

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AB - One more mechanism for regulating surface expression of MHC class II proteins in dendritic cells (an important process that regulates both tolerance and immunity) has been uncovered, polyubiquitination of Lys225 in the intracytoplasmic region and subsequent endocytosis and proteolysis (Omura-Hoshino et al., 2006; van Neil et al., 2006; Shin et al., 2006).

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U2 - 10.1016/j.immuni.2006.11.007

DO - 10.1016/j.immuni.2006.11.007

M3 - Short survey

C2 - 17174926

AN - SCOPUS:33845459284

SN - 1074-7613

VL - 25

SP - 857

EP - 859

JO - Immunity

JF - Immunity

IS - 6

ER -

The Ins and Outs of MHC Class II Proteins in Dendritic Cells

Abstract

ASJC Scopus subject areas

UN SDGs

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