The impact of the use of bioresorbable vascular scaffolds and drug-coated balloons in coronary bifurcation lesions

Mostafa Elwany, Amr Zaki, Azeem Latib, Luca Testa, Alfonso Ielasi, Davide Piraino, Salvatore Geraci, Tarek El Zawawy, Bernardo Cortese

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Background: Despite the improvement in techniques and tools, coronary lesions involving a bifurcation are still challenging and the outcome with drug-eluting stents is not always optimal. The role of bioresorbable vascular scaffolds (BVS) and drug-coated balloons (DCB) in this setting has not been adequately investigated yet. Results: From the databases of 6 italian centers with high proficiencies in newer technologies, we retrospectively collected all consecutive cases of coronary bifurcations managed or attempted with the implantation of at least one BVS in the main vessel and the use of one DCB in the side branch (SB). Primary study endpoint was the occurrence of major adverse cardiovascular events (MACE) at the longest available follow-up. Fourty patients fulfilled the enrollment criterion, 22.5% had diabetes and 50% an acute coronary syndrome. Average syntax score was 15.04 ± 7.18, all lesions were de novo, and 27 patients (67.5%) had a type 1,1,1 Medina lesion. Twenty-three lesions (57.5%) involved the proximal left anterior-descending artery/first diagonal branch. Only 32.5% of patients underwent an intravascular imaging-guided angioplasty. Average lesion length was 21.4 mm in the main vessel and 11.49 mm in the SB. MV was always predilated and BVS received a postdilation in 100% of the cases. In 42.5% of the cases, the DCB was used during final kissing balloon inflation, and in no cases, a stent/BVS was required in the SB. Procedural success was achieved in 100% of the cases. After an average follow-up of 15.5 (± 11.5) months, we observed no MACE with only one case of target vessel revasularization (2.5%). Conclusions: Management of coronary bifurcation lesions with the use of newer technologies including BVS and DCB seems feasible and effective at mid-term and long-term clinical follow-up.

Original languageEnglish (US)
Article number31
JournalEgyptian Heart Journal
Issue number1
StatePublished - Dec 1 2019


  • Bioresorbable vascular scaffolds (BVS)
  • Coronary bifurcation lesions
  • Drug-coated balloons (DCB)

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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