TY - JOUR
T1 - The electromotor system of the electric eel investigated with horseradish peroxidase as a retrograde tracer
AU - Bennett, Michael V.L.
AU - Sandri, Clara
N1 - Funding Information:
This work was supportedin part by grantsf rom the NationaIln stituteosf Health (NS 07412)a ndthe
PY - 1989/5/29
Y1 - 1989/5/29
N2 - The electromotor system of the electric eel, Electrophorus electricus, was studied by injection of horseradish peroxidase as a retrograde tracer. The electromotor neurons, which innervate the electrocytes, comprise a midline nucleus, largely dorsal to the spinal canal. Spinal motoneurons lie ventrolaterally. The electromotor and skeletal motor neuron populations correspond to the acetylcholinesterase-negative and -positive cells previously described. The medullary relay neurons were labeled following HRP injection into the spinal cord at a level where electromotor neurons occurred, but not after injection into the cord in the abdominal region rostral to these cells. Other medullary neurons, presumably bullospinal motor fibers, were labeled after both levels of spinal cord injection. The results suggest that these axosomatic synapses, which are electrically transmitting but morphologically mixed, take up retrograde tracers in a manner similar to chemical synapses and that tracer uptake is at least largely at terminal regions.
AB - The electromotor system of the electric eel, Electrophorus electricus, was studied by injection of horseradish peroxidase as a retrograde tracer. The electromotor neurons, which innervate the electrocytes, comprise a midline nucleus, largely dorsal to the spinal canal. Spinal motoneurons lie ventrolaterally. The electromotor and skeletal motor neuron populations correspond to the acetylcholinesterase-negative and -positive cells previously described. The medullary relay neurons were labeled following HRP injection into the spinal cord at a level where electromotor neurons occurred, but not after injection into the cord in the abdominal region rostral to these cells. Other medullary neurons, presumably bullospinal motor fibers, were labeled after both levels of spinal cord injection. The results suggest that these axosomatic synapses, which are electrically transmitting but morphologically mixed, take up retrograde tracers in a manner similar to chemical synapses and that tracer uptake is at least largely at terminal regions.
KW - Electric eel
KW - Electric organ
KW - Electrical synapse
KW - Horseradish peroxidase
KW - Morphologically mixed synapse
KW - Retrograde axonal transport
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U2 - 10.1016/0006-8993(89)90689-6
DO - 10.1016/0006-8993(89)90689-6
M3 - Article
C2 - 2743117
AN - SCOPUS:0024399550
SN - 0006-8993
VL - 488
SP - 22
EP - 30
JO - Brain research
JF - Brain research
IS - 1-2
ER -