The effect on the pullout strength by the timing of pedicle screw insertion after calcium phosphate cement injection

Woojin Cho, Chunhui Wu, Serkan Erkan, Matthew M. Kang, Amir A. Mehbod, Ensor E. Transfeldt

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


STUDY DESIGN: Biomechanical Cadaveric Study. OBJECTIVE: To characterize the pullout strength of calcium phosphate cement augmented screws between 0 and 6 minutes after cement injection. SUMMARY OF BACKGROUND DATA: Earlier studies with calcium phosphate cement on pedicle screws inserted into a metal mold or sawbone have shown that the augmentation strength can be affected by the time between cement injection and screw insertion. However, these studies only compared soft cement to completely hardened cement with extended waiting times. These extended waiting times are impractical in live spinal surgeries. METHODS: Twenty-four pedicle screws were inserted and pulled out axially from cadaveric bone to make revision models. The 24 screw holes were randomly divided into 4 groups, with each group having 6 holes. For each group, identical pedicle screws were inserted at 0, 2, 4, and 6 minutes after injection with bioresorbable calcium phosphate cement (CPC). After 24 hours, the augmented screws were pulled out axially and their pullout strengths were compared. RESULTS: The difference between secondary pullout strength and primary pullout strength increased up to 4 minutes after cement injection but decreased after 6 minutes but without statistical difference among the 4 time settings (P>0.3). CONCLUSIONS: The augmented screws had similar fixation strength regardless of the time between cement mixture and screw insertion as long as they are inserted within 6 minutes. Augmentation power tends to increase up to 4 minutes after cement injection but decreases after 6 minutes.

Original languageEnglish (US)
Pages (from-to)116-120
Number of pages5
JournalJournal of Spinal Disorders and Techniques
Issue number2
StatePublished - Apr 2011
Externally publishedYes


  • bioabsorbable
  • calcium phosphate cement
  • cement augmentation
  • pedicle screw
  • pullout strength

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine
  • Clinical Neurology


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