TY - JOUR
T1 - The Effect of Vibration on Pain during Intravenous Injection of Propofol
T2 - A Randomized Controlled Trial
AU - Hwang, Lyahn K.
AU - Nash, David W.
AU - Yedlin, Adam
AU - Greige, Nicolas
AU - Larios-Valencia, Jessie
AU - Choice, Curtis
AU - Pothula, Aravind
N1 - Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.
PY - 2021/7/1
Y1 - 2021/7/1
N2 - Purpose Pain is a common side effect of intravenous injection of propofol. We conducted a randomized, prospective, single-blinded controlled trial to assess the efficacy of vibration analgesia on pain during propofol infusion in ambulatory surgery. Methods After institutional review board approval, 100 patients undergoing elective ambulatory surgery with general anesthesia were randomized into 2 groups. A control group (n = 50) consisted of patients who received infusion of propofol without vibration analgesia. A treatment group (n = 50) consisted of patients who received infusion of propofol with vibration analgesia using the Buzzy device. Pain was assessed using a 4-point pain manifestation scale scored by 2 independent, blinded observers. Results Participants in the treatment group with vibration analgesia were 0.47 times less likely (95% confidence interval, 0.24-0.94; P = 0.03) to experience any pain than the control group. The median summative pain score in the treatment group was significantly less than that of the control group [1 (interquartile range, 1-2) vs 2 (interquartile range, 2-4); P < 0.01] among participants who experienced any pain. Agreement between the 2 blinded observers regarding pain scores was excellent with κw = 0.82 (P < 0.001). Age, sex, body mass index, needle location or size, and medication doses did not differ significantly between the 2 groups. Conclusion Vibration analgesia is an effective, low-risk modality that reduces the pain of intravenous propofol injection in general anesthesia.
AB - Purpose Pain is a common side effect of intravenous injection of propofol. We conducted a randomized, prospective, single-blinded controlled trial to assess the efficacy of vibration analgesia on pain during propofol infusion in ambulatory surgery. Methods After institutional review board approval, 100 patients undergoing elective ambulatory surgery with general anesthesia were randomized into 2 groups. A control group (n = 50) consisted of patients who received infusion of propofol without vibration analgesia. A treatment group (n = 50) consisted of patients who received infusion of propofol with vibration analgesia using the Buzzy device. Pain was assessed using a 4-point pain manifestation scale scored by 2 independent, blinded observers. Results Participants in the treatment group with vibration analgesia were 0.47 times less likely (95% confidence interval, 0.24-0.94; P = 0.03) to experience any pain than the control group. The median summative pain score in the treatment group was significantly less than that of the control group [1 (interquartile range, 1-2) vs 2 (interquartile range, 2-4); P < 0.01] among participants who experienced any pain. Agreement between the 2 blinded observers regarding pain scores was excellent with κw = 0.82 (P < 0.001). Age, sex, body mass index, needle location or size, and medication doses did not differ significantly between the 2 groups. Conclusion Vibration analgesia is an effective, low-risk modality that reduces the pain of intravenous propofol injection in general anesthesia.
KW - analgesia
KW - induction
KW - propofol
KW - vibration
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U2 - 10.1097/SAP.0000000000002827
DO - 10.1097/SAP.0000000000002827
M3 - Article
C2 - 33833179
AN - SCOPUS:85111788966
SN - 0148-7043
VL - 87
SP - S36-S39
JO - Annals of Plastic Surgery
JF - Annals of Plastic Surgery
IS - 1
ER -