Abstract
As recently as ten years ago the opiate receptor was demonstrated biochemically for the first time and it was assumed that opiate drugs produced their psychotropic actions through a unique opiate receptor. Today compelling evidence from behavioral, pharmacological and biochemical studies indicates the existence of at least four receptor classes, μ, δ, κ and σ. The constellation of neuropharmacological actions of opiates as well as those of the three major classes of opioid peptides (β-endorphin, the enkephalins and dynorphin-related peptides) are now thought to occur by an interaction with a combination of these sites.
Original language | English (US) |
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Pages (from-to) | 160-162,163-164 |
Journal | Trends in Neurosciences |
Volume | 7 |
Issue number | 5 |
DOIs | |
State | Published - May 1984 |
ASJC Scopus subject areas
- General Neuroscience