The battle over inhibitory synaptic plasticity in satiety brain circuits

Thomas J. Younts, Pablo E. Castillo

Research output: Contribution to journalShort surveypeer-review

Abstract

The synaptic basis underlying food intake is poorly understood. New research shows that an animal's satiety state dictates the polarity of long-term inhibitory synaptic plasticity in the hypothalamus, which is mediated by an activity-dependent competition between endocannabinoid and nitric oxide signaling.

Original languageEnglish (US)
Pages (from-to)385-387
Number of pages3
JournalNeuron
Volume71
Issue number3
DOIs
StatePublished - Aug 11 2011

ASJC Scopus subject areas

  • General Neuroscience

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