TY - JOUR
T1 - The Antitachycardia Pacing ICD
T2 - Impact on Patient Selection and Outcome
AU - GROSS, JAY N.
AU - SACKSTEIN, ROBERT D.
AU - SONG, SUSAN L.
AU - GHANG, CHEE JEN
AU - KAWINISHI, DAVID T.
AU - FURMAN, SEYMOUR
PY - 1993/1
Y1 - 1993/1
N2 - Implantable cardioverter defibrillators (ICD) currently undergoing clinical investigation incorporate antitachycardia pacing capabilities, but little is known about their effect on patient selection and outcome. The Bilitch registry database was reviewed to compare the 1,553 patients who initially received standard devices with the 242 patients initially implanted with antitachycardia pacing ICDs (ANT). Baseline characteristics including mean age, ejection fraction, sex, type of cardiac disease, and percent presenting with sudden cardiac death were reviewed. Cumulative first shock occurrence and survival from arrhythmic and ail cause mortality were calculated for the two groups. Results: Patient characteristics were similar in the two groups except that the ANT population had a greater male predominance and initially presented with a lower sudden cardiac death incidence (P < 0.05). Cumulative occurrence of first shock was significantly lower in the ANT group up to 24 months of follow‐up (28% vs 36%, P < 0.05). ANT group survival from arrhythmic death (99% vs 96%) and all cause mortality (89% vs 94%) was significantly higher at 24 months of follow‐up (P < 0.05). Conclusions: The addition of antitachycardia pacing to ICD therapy appears to significantly limit the occurrence of first ICD shock without adversely affecting mortality in a patient population similar to those implanted with standard ICDs.
AB - Implantable cardioverter defibrillators (ICD) currently undergoing clinical investigation incorporate antitachycardia pacing capabilities, but little is known about their effect on patient selection and outcome. The Bilitch registry database was reviewed to compare the 1,553 patients who initially received standard devices with the 242 patients initially implanted with antitachycardia pacing ICDs (ANT). Baseline characteristics including mean age, ejection fraction, sex, type of cardiac disease, and percent presenting with sudden cardiac death were reviewed. Cumulative first shock occurrence and survival from arrhythmic and ail cause mortality were calculated for the two groups. Results: Patient characteristics were similar in the two groups except that the ANT population had a greater male predominance and initially presented with a lower sudden cardiac death incidence (P < 0.05). Cumulative occurrence of first shock was significantly lower in the ANT group up to 24 months of follow‐up (28% vs 36%, P < 0.05). ANT group survival from arrhythmic death (99% vs 96%) and all cause mortality (89% vs 94%) was significantly higher at 24 months of follow‐up (P < 0.05). Conclusions: The addition of antitachycardia pacing to ICD therapy appears to significantly limit the occurrence of first ICD shock without adversely affecting mortality in a patient population similar to those implanted with standard ICDs.
KW - antitachycardia pacing
KW - implantable defibrillator
KW - sudden death
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U2 - 10.1111/j.1540-8159.1993.tb01555.x
DO - 10.1111/j.1540-8159.1993.tb01555.x
M3 - Article
C2 - 7681565
AN - SCOPUS:0027410969
SN - 0147-8389
VL - 16
SP - 165
EP - 169
JO - Pacing and Clinical Electrophysiology
JF - Pacing and Clinical Electrophysiology
IS - 1
ER -