Tet1 Suppresses p21 to Ensure Proper Cell Cycle Progression in Embryonic Stem Cells

Keyphrases

• Embryonic Stem Cells 100%
• Cell Cycle Progression 100%
• Ten-eleven Translocation 1 (TET1) 100%
• Mouse ESCs 35%
• Non-catalytic 14%
• Enhancer of Zeste Homolog 2 (EZH2) 14%
• Stem Cell Proliferation 14%
• P21 Promoter 14%
• Catalytic Role 14%
• Cell Cycle Proliferation 14%
• Gene Expression 7%
• Cell-to-cell 7%
• Polycomb Repressive Complex 2 (PRC2) 7%
• Chromatin 7%
• Occupancy 7%
• H3K27me3 7%
• Mouse Embryonic Stem Cells (mESCs) 7%
• 5-hydroxymethylcytosine (5hmC) 7%
• Knockdown 7%
• Enzymatic Activity 7%
• Catalytic Activity 7%
• Cyclin-dependent Kinase Inhibitor p21 7%
• Stem Cell Differentiation 7%
• Pluripotency 7%
• Epigenetic Regulators 7%
• Catalytic mutant 7%
• Direct Target 7%
• DNA Demethylation 7%
• CDKN1A 7%
• Repressive Histone Marks 7%
• DNA Methylation Profiling 7%
• Stem Cell Pluripotency 7%
• DNA Dioxygenase 7%
• Transferases 7%
• H3K27 Trimethylation 7%

Biochemistry, Genetics and Molecular Biology

• Embryonic Stem Cell 100%
• Cell Cycle Progression 100%
• P21 100%
• Promoter Region 28%
• Cell Proliferation 28%
• Wild Type 14%
• DNA Methylation 14%
• Gene Expression 14%
• Transferase 14%
• Enzyme Activity 14%
• Cyclin-Dependent Kinase 14%
• DNA Demethylation 14%
• Chromatin 14%
• PRC2 14%
• Histone 14%
• Enzymatic Activity 14%
• 5-Methylcytosine 14%
• Dioxygenase 14%