Systemic sclerosis with renal crisis and pericardial effusion

Kalyan Prudhvi, Jayasree Jonnadula, Gurusaravanan Kutti Sridharan, Mary Dominguez

Research output: Contribution to journalArticlepeer-review


Scleroderma renal crisis occurs in 10% of patients with systemic sclerosis carrying a poor prognosis. A kidney biopsy is consistent with thrombotic microangiopathy (TMA) with clinical findings discerning it from other TMAs. Progression to ESRD occurs in 50% of patients which can lead to further complications necessitating emergent interventions including dialysis. Patients with scleroderma can have pericardial involvement with tamponade physiology requiring intervention such as pericardiocentesis.

Original languageEnglish (US)
Pages (from-to)3656-3657
Number of pages2
JournalClinical Case Reports
Issue number12
StatePublished - Dec 2020


  • cardiac tamponade
  • pericardial effusion
  • renal crisis
  • scleroderma
  • thrombotic microangiopathy

ASJC Scopus subject areas

  • Medicine(all)


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