TY - JOUR
T1 - Synthesis and characterization of a series of hydrophobic antitumor bis(carboxylato) (1, 2-diaminocyclohexane) platinum(ii) complexes
AU - Al-Baker, Salaam
AU - Perez-Soler, Roman
AU - Khokhar, Abdul R.
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1993/6/1
Y1 - 1993/6/1
N2 - A series of hydrophobic platinum(II) complexes of the type (DACH)PtX2(where DACH = various isomeric forms of 1, 2-diaminocyclohexane and X = pentanoato, hexanoato, heptanoato, octanoato, nonanoato, decanoato, unidecanoato, laurato, tridecanoato, myristato, pentadecanoato, palmitato, heptadecanoato, or stearato) has been synthesized and characterized using elemental analysis, infrared spectra and nuclear magnetic resonance (13C{1H} and195Pt{1H}). The complexes have been prepared as potential antitumor agents for liposome entrapment.
AB - A series of hydrophobic platinum(II) complexes of the type (DACH)PtX2(where DACH = various isomeric forms of 1, 2-diaminocyclohexane and X = pentanoato, hexanoato, heptanoato, octanoato, nonanoato, decanoato, unidecanoato, laurato, tridecanoato, myristato, pentadecanoato, palmitato, heptadecanoato, or stearato) has been synthesized and characterized using elemental analysis, infrared spectra and nuclear magnetic resonance (13C{1H} and195Pt{1H}). The complexes have been prepared as potential antitumor agents for liposome entrapment.
KW - 2-diaminocyclohexane carboxylate liposomes hydrophobic synthesis
KW - Platinum 1
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U2 - 10.1080/00958979308037119
DO - 10.1080/00958979308037119
M3 - Article
AN - SCOPUS:0000944043
SN - 0095-8972
VL - 29
SP - 1
EP - 6
JO - Journal of Coordination Chemistry
JF - Journal of Coordination Chemistry
IS - 1-2
ER -