TY - JOUR
T1 - Summary of presentations at the NIH/NIAID new humanized rodent models 2007 workshop
AU - Goldstein, Harris
N1 - Funding Information:
This document represents a summary of presentations made during the New Humanized Rodent Model Workshop organized and supported by the Division of AIDS, the National Institute of Allergy and Infectious Diseases, the National Institutes of Health. The views contained in this report are those of the presenters and do not necessarily reflect the views of the Division of AIDS, the National Institute of Allergy and Infectious Diseases, the National Institutes of Health, or any other governmental agency. Presenters at the workshop were: Drs. Harris Goldstein, Ramesh Akkina, Victor Garcia, Oliver T. Keppler, Vineet KewalRamani, Dan Littman, Jeremy Luban, Leonard D. Shultz, Roberto F. Speck, Cheryl Stoddart, and Lishan Su. This work was supported in part by the Einstein/MMC Center for AIDS Research funded by the National Institutes of Health (NIH AI-51519).
PY - 2008/1/31
Y1 - 2008/1/31
N2 - It has long been recognized that a small animal model susceptible to HIV-1 infection with a functional immune system would be extremely useful in the study of HIV/AIDS pathogenesis and for the evaluation of vaccine and therapeutic strategies to combat this disease. By early 2007, a number of reports on various rodent models capable of being infected by and responding to HIV including some with a humanized immune system were published. The New Humanized Rodent Model Workshop, organized by the Division of AIDS (DAIDS), National Institute Allergy and Infection Diseases (NIAID), NIH, was held on September 24, 2007 at Bethesda for the purpose of bringing together key model developers and potential users. This report provides a synopsis of the presentations that discusses the current status of development and use of rodent models to evaluate the pathogenesis of HIV infection and to assess the efficacy of vaccine and therapeutic strategies including microbicides to prevent and/or treat HIVinfection.
AB - It has long been recognized that a small animal model susceptible to HIV-1 infection with a functional immune system would be extremely useful in the study of HIV/AIDS pathogenesis and for the evaluation of vaccine and therapeutic strategies to combat this disease. By early 2007, a number of reports on various rodent models capable of being infected by and responding to HIV including some with a humanized immune system were published. The New Humanized Rodent Model Workshop, organized by the Division of AIDS (DAIDS), National Institute Allergy and Infection Diseases (NIAID), NIH, was held on September 24, 2007 at Bethesda for the purpose of bringing together key model developers and potential users. This report provides a synopsis of the presentations that discusses the current status of development and use of rodent models to evaluate the pathogenesis of HIV infection and to assess the efficacy of vaccine and therapeutic strategies including microbicides to prevent and/or treat HIVinfection.
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U2 - 10.1186/1742-6405-5-3
DO - 10.1186/1742-6405-5-3
M3 - Review article
C2 - 18237418
AN - SCOPUS:41549135641
SN - 1742-6405
VL - 5
JO - AIDS Research and Therapy
JF - AIDS Research and Therapy
M1 - 3
ER -
