Sudden onset blindness in sickle cell disease due to retinal artery occlusion

Robert I. Liem; Diane M. Calamaras; Manpreet S. Chhabra; Beatrice Files; Caterina P. Minniti; Alexis A. Thompson

doi:10.1002/pbc.21152

Sudden onset blindness in sickle cell disease due to retinal artery occlusion

Robert I. Liem, Diane M. Calamaras, Manpreet S. Chhabra, Beatrice Files, Caterina P. Minniti, Alexis A. Thompson

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Central retinal artery occlusion (CRAO) is a rare and potentially devastating cause of acute blindness in sickle cell disease (SCD) that is unique compared to classic sickle retinopathy. Few details related to this complication in SCD are known, including its risk factors, pathogenesis, presentation, treatment and outcomes. We present three patients with SCD and retinal artery occlusion. The overall variability in clinical presentation, treatment and prognosis reported in the literature underscores the need for a greater understanding of these factors as they relate to this complication in SCD.

Original language	English (US)
Pages (from-to)	624-627
Number of pages	4
Journal	Pediatric Blood and Cancer
Volume	50
Issue number	3
DOIs	https://doi.org/10.1002/pbc.21152
State	Published - Mar 2008
Externally published	Yes

Keywords

Macular ischemia
Retinal artery occlusion
Sickle cell disease
Sudden blindness

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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abstract = "Central retinal artery occlusion (CRAO) is a rare and potentially devastating cause of acute blindness in sickle cell disease (SCD) that is unique compared to classic sickle retinopathy. Few details related to this complication in SCD are known, including its risk factors, pathogenesis, presentation, treatment and outcomes. We present three patients with SCD and retinal artery occlusion. The overall variability in clinical presentation, treatment and prognosis reported in the literature underscores the need for a greater understanding of these factors as they relate to this complication in SCD.",

keywords = "Macular ischemia, Retinal artery occlusion, Sickle cell disease, Sudden blindness",

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AU - Calamaras, Diane M.

AU - Chhabra, Manpreet S.

AU - Files, Beatrice

AU - Minniti, Caterina P.

AU - Thompson, Alexis A.

PY - 2008/3

Y1 - 2008/3

N2 - Central retinal artery occlusion (CRAO) is a rare and potentially devastating cause of acute blindness in sickle cell disease (SCD) that is unique compared to classic sickle retinopathy. Few details related to this complication in SCD are known, including its risk factors, pathogenesis, presentation, treatment and outcomes. We present three patients with SCD and retinal artery occlusion. The overall variability in clinical presentation, treatment and prognosis reported in the literature underscores the need for a greater understanding of these factors as they relate to this complication in SCD.

AB - Central retinal artery occlusion (CRAO) is a rare and potentially devastating cause of acute blindness in sickle cell disease (SCD) that is unique compared to classic sickle retinopathy. Few details related to this complication in SCD are known, including its risk factors, pathogenesis, presentation, treatment and outcomes. We present three patients with SCD and retinal artery occlusion. The overall variability in clinical presentation, treatment and prognosis reported in the literature underscores the need for a greater understanding of these factors as they relate to this complication in SCD.

KW - Macular ischemia

KW - Retinal artery occlusion

KW - Sickle cell disease

KW - Sudden blindness

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Sudden onset blindness in sickle cell disease due to retinal artery occlusion

Abstract

Keywords

ASJC Scopus subject areas

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