Substrate-protein interaction in human tryptophan dioxygenase: The critical role of H76

Medicine & Life Sciences

• Tryptophan Oxygenase 68%
• Hemeproteins 68%
• Dioxygenases 63%
• Tryptophan 47%
• Indoleamine-Pyrrole 2,3,-Dioxygenase 20%
• Catalytic Domain 19%
• Kynurenine 19%
• indole 19%
• Proteins 16%
• Ammonium Compounds 9%
• Mutation 8%
• Histidine 8%
• Hydrophobic and Hydrophilic Interactions 8%
• Serine 7%
• Cats 6%
• Water 4%

Engineering & Materials Science

• Hemeproteins 100%
• Proteins 40%
• Substrates 31%
• Oxidation 12%
• Electronic properties 11%
• Assays 8%
• Catalysts 6%
• Water 3%

Chemical Compounds

• Tryptophan 41%
• Indole 11%
• Mutation 10%
• N-Formylkynurenine 10%
• Kynurenine 9%
• Histidine 6%
• Serine 5%
• Oxidation Reaction 5%
• Electronic Property 5%
• Resonance 5%
• Ammonium 4%
• Protein 2%