Subintimal tracking and re-entry technique with contrast guidance: A safer approach

Mauro Carlino, Cosmo Godino, Azeem Latib, Jeffrey W. Moses, Antonio Colombo

Research output: Contribution to journalArticlepeer-review

88 Scopus citations


Objectives: To assess the procedural and clinical outcomes from a modified subintimal tracking and re-entry (STAR) procedure performed using contrast guidance. Background: Previous data showed that recanalizing a chronic total occlusion (CTO) with the STAR technique was possible. However, this technique was considered difficult and therefore has only been adopted by a limited number of experienced operators. Methods: Patients (n 5 68) with a CTO of a native coronary artery treated by a single operator with this technique were included. Results: The right coronary artery was involved in 79.4%, the morphology was blunt in 77.9%, and CTO length was longer than 20 mm in 67.6%. Angiographic success rate was 80.9% with a 70.6% rate of complete recanalization. Stent implantation was performed in 82.3% of cases, with drug-eluting stents (DES) implanted in the majority (92.7%). Procedural complications occurred in 10.3% of cases. There were no episodes of myocardial infarction during follow-up, with 1 case (1.5%) of cardiac death. There were no cases of definite or probable stent thrombosis, and there was 1 (1.5%) possible stent thrombosis. The overall rate of in-segment binary restenosis was 44.7%, and target lesion revascularization (TLR) was performed in 25% of lesions. The rate of TLR in lesions treated with DES was 29.4% and in those treated with bare-metal stents was 50%. Conclusion: The contrast-guided STAR technique appears to be feasible and relatively safe. However, this procedure is limited by a high rate of restenosis even with DES, and a second procedure may be necessary to obtain a definitive result.

Original languageEnglish (US)
Pages (from-to)790-796
Number of pages7
JournalCatheterization and Cardiovascular Interventions
Issue number6
StatePublished - Nov 15 2008
Externally publishedYes


  • Chronic total occlusion
  • Drug-eluting stent
  • Major adverse cardiac events
  • Percutaneous coronary intervention

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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