Statistical methods in cancer epidemiological studies

Xiaonan Xue, Donald R. Hoover

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations


In this chapter, we discuss statistical methods for various study designs that are commonly used in epidemiological research and particularly in cancer epidemiological research. After a brief review of basic concepts in epidemiological studies, statistical methods for case-control studies and cohort studies are discussed. Statistical methods for nested case-control and case-cohort studies, which have been increasingly used in cancer epidemiology, also are discussed. This chapter is designed for cancer epidemiologists who understand basic statistical methods for commonly used epidemiological study designs and are able to initiate power and sample size calculations. Therefore, this chapter emphasizes newly developed statistical methods for epidemiological studies as well as study planning.

Original languageEnglish (US)
Title of host publicationCancer Epidemiology
Subtitle of host publicationVolume I: Host Susceptibility Factors
EditorsMukesh Verma
Number of pages34
StatePublished - Feb 23 2009

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745


  • Case-cohort study
  • Case-control study
  • Cohort study
  • Matched case-control study
  • Nested case-control study

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics


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