TY - JOUR
T1 - Stability of Polyadenylated RNA in Differentiating Myogenic Cells
AU - SINGER, Robert H.
AU - KESSLER‐ICEKSON, Gania
PY - 1978/8
Y1 - 1978/8
N2 - Three independent methods of measurement showed that cytoplasmic polyadenylated RNA from the differentiating myogenic cell line L8 consists of two main populations with regard to stability, one with a half‐life of less than 4 h and the other with a half‐life of 17–54 h. Similar results were obtained in the presence and absence of actinomycin D. During the fusion of mononucleated myoblasts into multinucleated fibers, there was an increase in both the steady‐state pool of the more stable polyadenylated RNA and the proportion of stable polyadenylated RNA synthesized in pulse labelling.
AB - Three independent methods of measurement showed that cytoplasmic polyadenylated RNA from the differentiating myogenic cell line L8 consists of two main populations with regard to stability, one with a half‐life of less than 4 h and the other with a half‐life of 17–54 h. Similar results were obtained in the presence and absence of actinomycin D. During the fusion of mononucleated myoblasts into multinucleated fibers, there was an increase in both the steady‐state pool of the more stable polyadenylated RNA and the proportion of stable polyadenylated RNA synthesized in pulse labelling.
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U2 - 10.1111/j.1432-1033.1978.tb12461.x
DO - 10.1111/j.1432-1033.1978.tb12461.x
M3 - Article
C2 - 689025
AN - SCOPUS:0018104262
SN - 0014-2956
VL - 88
SP - 395
EP - 402
JO - European Journal of Biochemistry
JF - European Journal of Biochemistry
IS - 2
ER -