Since the discovery of Prp16, a spliceosomal ATPase that alters the fidelity of splicing, many other ATPases associated with the spliceosome have been postulated to work similarly. The finding that Prp22, a DEAH-box ATPase, functions as a fidelity factor for the second step of splicing supports this hypothesis.
|Original language||English (US)|
|Number of pages||3|
|Journal||Nature Structural and Molecular Biology|
|State||Published - Jun 26 2006|
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology