Abstract
Since the discovery of Prp16, a spliceosomal ATPase that alters the fidelity of splicing, many other ATPases associated with the spliceosome have been postulated to work similarly. The finding that Prp22, a DEAH-box ATPase, functions as a fidelity factor for the second step of splicing supports this hypothesis.
Original language | English (US) |
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Pages (from-to) | 472-474 |
Number of pages | 3 |
Journal | Nature Structural and Molecular Biology |
Volume | 13 |
Issue number | 6 |
DOIs | |
State | Published - Jun 26 2006 |
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology