TY - JOUR
T1 - Spectrum of peripheral retinal ischemia in Wyburn-Mason syndrome
AU - Fortes, Blake
AU - Lin, James
AU - Prakhunhungsit, Supalert
AU - Mendoza-Santiesteban, Carlos
AU - Berrocal, Audina M.
N1 - Funding Information:
NIH Center Core Grant P30EY014801 and Research to Prevent Blindness Unrestricted Grant.
Publisher Copyright:
© 2020
PY - 2020/6
Y1 - 2020/6
N2 - Purpose: We report two cases of Wyburn-Mason syndrome that illustrate the spectrum of peripheral retinal ischemia seen in this condition. Observations: A 12-year-old female presented with a retinal arteriovenous malformation and sclerotic vessels associated with retinal ischemia on fluorescein angiography, as well as an ipsilateral ophthalmic arteriovenous malformation on magnetic resonance imaging. An 11-year-old male presented with retinal vascular engorgement and tortuosity along with a central retinal vein occlusion and secondary neovascularization. Conclusions and Importance: Retinal ischemia in Wyburn-Mason syndrome is heterogeneous and may be progressive, with secondary complications that result in neovascularization. Furthermore, it is necessary to recognize that this is a systemic condition that requires neurological evaluation.
AB - Purpose: We report two cases of Wyburn-Mason syndrome that illustrate the spectrum of peripheral retinal ischemia seen in this condition. Observations: A 12-year-old female presented with a retinal arteriovenous malformation and sclerotic vessels associated with retinal ischemia on fluorescein angiography, as well as an ipsilateral ophthalmic arteriovenous malformation on magnetic resonance imaging. An 11-year-old male presented with retinal vascular engorgement and tortuosity along with a central retinal vein occlusion and secondary neovascularization. Conclusions and Importance: Retinal ischemia in Wyburn-Mason syndrome is heterogeneous and may be progressive, with secondary complications that result in neovascularization. Furthermore, it is necessary to recognize that this is a systemic condition that requires neurological evaluation.
KW - Arteriovenous malformation
KW - Central retinal vein occlusion
KW - Peripheral retinal ischemia
KW - Wyburn-mason syndrome
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U2 - 10.1016/j.ajoc.2020.100640
DO - 10.1016/j.ajoc.2020.100640
M3 - Article
AN - SCOPUS:85080981229
SN - 2451-9936
VL - 18
JO - American Journal of Ophthalmology Case Reports
JF - American Journal of Ophthalmology Case Reports
M1 - 100640
ER -