Spatial and temporal sequence of corneal crystal deposition in nephropathic cystinosis

Ronald B. Melles; Jerry A. Schneider; Narsing A. Rao; Barrett Katz

doi:10.1016/0002-9394(87)90171-1

Spatial and temporal sequence of corneal crystal deposition in nephropathic cystinosis

Ronald B. Melles, Jerry A. Schneider, Narsing A. Rao, Barrett Katz

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

We studied 15 patients with infantile nephropathic cystinosis. We found that anterior corneal cystine crystal deposition began early in life and proceeded posteriorly as the patient aged; deposition advanced more rapidly in the periphery. Ultrastructural analysis of a corneal button obtained from a 20-year-old patient undergoing corneal transplantation confirmed our clinical observations that crystals were deposited throughout the entire central stroma.

Original language	English (US)
Pages (from-to)	598-604
Number of pages	7
Journal	American journal of ophthalmology
Volume	104
Issue number	6
DOIs	https://doi.org/10.1016/0002-9394(87)90171-1
State	Published - Dec 1987
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

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10.1016/0002-9394(87)90171-1

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title = "Spatial and temporal sequence of corneal crystal deposition in nephropathic cystinosis",

abstract = "We studied 15 patients with infantile nephropathic cystinosis. We found that anterior corneal cystine crystal deposition began early in life and proceeded posteriorly as the patient aged; deposition advanced more rapidly in the periphery. Ultrastructural analysis of a corneal button obtained from a 20-year-old patient undergoing corneal transplantation confirmed our clinical observations that crystals were deposited throughout the entire central stroma.",

author = "Melles, {Ronald B.} and Schneider, {Jerry A.} and Rao, {Narsing A.} and Barrett Katz",

year = "1987",

month = dec,

doi = "10.1016/0002-9394(87)90171-1",

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T1 - Spatial and temporal sequence of corneal crystal deposition in nephropathic cystinosis

AU - Melles, Ronald B.

AU - Schneider, Jerry A.

AU - Rao, Narsing A.

AU - Katz, Barrett

PY - 1987/12

Y1 - 1987/12

N2 - We studied 15 patients with infantile nephropathic cystinosis. We found that anterior corneal cystine crystal deposition began early in life and proceeded posteriorly as the patient aged; deposition advanced more rapidly in the periphery. Ultrastructural analysis of a corneal button obtained from a 20-year-old patient undergoing corneal transplantation confirmed our clinical observations that crystals were deposited throughout the entire central stroma.

AB - We studied 15 patients with infantile nephropathic cystinosis. We found that anterior corneal cystine crystal deposition began early in life and proceeded posteriorly as the patient aged; deposition advanced more rapidly in the periphery. Ultrastructural analysis of a corneal button obtained from a 20-year-old patient undergoing corneal transplantation confirmed our clinical observations that crystals were deposited throughout the entire central stroma.

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JO - American journal of ophthalmology

JF - American journal of ophthalmology

IS - 6

ER -

Spatial and temporal sequence of corneal crystal deposition in nephropathic cystinosis

Abstract

ASJC Scopus subject areas

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