Soft tissue metastasis as initial manifestation of pleural malignant mesothelioma: A case report

Javier A. Laurini, Teresa Castiglioni, Boris Elsner, Alejandra Avagnina, Santiago Ferreiro, Marta Belloti

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Distant metastases of pleural malignant mesothelioma (MM) are infrequent. We report a case of MM that presented as a skeletal muscle metastasis. This type of presentation has not been previously reported. A 38- year-old male complained about a mass in his fight forearm. The tumor showed the histologic pattern, immunohistochemical phenotype, and ultrastructural features of an MM. In the clinical work-up, the x-ray film and computed tomography scan demonstrated pleural effusion and diffuse pleural thickening in the right hemithorax. The pleural biopsy showed an epithelial MM. The patient died from local progression of the disease 6 months after the diagnosis. No other distant metastases were clinically evident. Our case shows the importance of including MM in the differential diagnosis of metastatic neoplasms in skeletal muscle and the usefulness of ancillary techniques in the diagnosis of mesothelial neoplasms.

Original languageEnglish (US)
Pages (from-to)39-44
Number of pages6
JournalInternational Journal of Surgical Pathology
Issue number1
StatePublished - Jan 1999
Externally publishedYes


  • Immunohistochemistry
  • Malignant mesothelioma
  • Metastases
  • Skeletal muscte
  • Soft tissue

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine


Dive into the research topics of 'Soft tissue metastasis as initial manifestation of pleural malignant mesothelioma: A case report'. Together they form a unique fingerprint.

Cite this