SnapShot: Chromosome organization

Rachel Patton McCord; Yang Xu; Heng Li; Priyojit Das; Rebeca San Martin

doi:10.1016/j.molcel.2022.05.020

SnapShot: Chromosome organization

Rachel Patton McCord, Yang Xu, Heng Li, Priyojit Das, Rebeca San Martin

Research output: Contribution to journal › Comment/debate › peer-review

1 Scopus citations

Abstract

Chromosomes in higher eukaryotes are folded at different length scales into loop extrusion domains, spatial compartments, and chromosome territories and exhibit interactions with nuclear structures such as the lamina. Microscopic methods can probe this structure by measuring positions of chromosomes in the nuclear space in individual cells, while sequencing-based contact capture approaches can report the frequency of contacts of different regions within these structural layers. To view this SnapShot, open or download the PDF.

Original language	English (US)
Pages (from-to)	2350-2350.e1
Journal	Molecular Cell
Volume	82
Issue number	12
DOIs	https://doi.org/10.1016/j.molcel.2022.05.020
State	Published - Jun 16 2022
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1016/j.molcel.2022.05.020

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title = "SnapShot: Chromosome organization",

abstract = "Chromosomes in higher eukaryotes are folded at different length scales into loop extrusion domains, spatial compartments, and chromosome territories and exhibit interactions with nuclear structures such as the lamina. Microscopic methods can probe this structure by measuring positions of chromosomes in the nuclear space in individual cells, while sequencing-based contact capture approaches can report the frequency of contacts of different regions within these structural layers. To view this SnapShot, open or download the PDF.",

author = "McCord, {Rachel Patton} and Yang Xu and Heng Li and Priyojit Das and {San Martin}, Rebeca",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",

year = "2022",

month = jun,

day = "16",

doi = "10.1016/j.molcel.2022.05.020",

language = "English (US)",

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pages = "2350--2350.e1",

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TY - JOUR

T1 - SnapShot

T2 - Chromosome organization

AU - McCord, Rachel Patton

AU - Xu, Yang

AU - Li, Heng

AU - Das, Priyojit

AU - San Martin, Rebeca

PY - 2022/6/16

Y1 - 2022/6/16

N2 - Chromosomes in higher eukaryotes are folded at different length scales into loop extrusion domains, spatial compartments, and chromosome territories and exhibit interactions with nuclear structures such as the lamina. Microscopic methods can probe this structure by measuring positions of chromosomes in the nuclear space in individual cells, while sequencing-based contact capture approaches can report the frequency of contacts of different regions within these structural layers. To view this SnapShot, open or download the PDF.

AB - Chromosomes in higher eukaryotes are folded at different length scales into loop extrusion domains, spatial compartments, and chromosome territories and exhibit interactions with nuclear structures such as the lamina. Microscopic methods can probe this structure by measuring positions of chromosomes in the nuclear space in individual cells, while sequencing-based contact capture approaches can report the frequency of contacts of different regions within these structural layers. To view this SnapShot, open or download the PDF.

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U2 - 10.1016/j.molcel.2022.05.020

DO - 10.1016/j.molcel.2022.05.020

M3 - Comment/debate

C2 - 35714589

AN - SCOPUS:85131927857

SN - 1097-2765

VL - 82

SP - 2350-2350.e1

JO - Molecular Cell

JF - Molecular Cell

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ER -

SnapShot: Chromosome organization

Abstract

ASJC Scopus subject areas

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