Small intestinal bacterial overgrowth syndrome

T. S. Dharmarajan, C. S. Pitchumoni

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Small intestinal bacterial overgrowth (SIBO) is an underrecognized cause of malabsorption in the geriatric population, characterized by the excessive growth of bacteria in the small bowel, sometimes bearing resemblance to colonic flora. Age is a predisposing factor; however additional comorbidity such as diabetes, systemic sclerosis, Parkinson's disease, irritable bowel syndrome, and a variety of stasis syndromes such as blind loops, diverticulae, and fistulae are likely to be the basis. Medications that affect immune function and excessive use of PPIs are recognized causes. Diagnosis is based on demonstration of positive duodenal or jejunal aspirate cultures and breath tests. Management typically involves a short course of antibiotics; however recurrences often follow months following antibiotic therapy necessitating repeat courses.

Original languageEnglish (US)
Title of host publicationGeriatric Gastroenterology
PublisherSpringer New York
Number of pages6
ISBN (Electronic)9781441916235
ISBN (Print)9781441916228
StatePublished - Jan 1 2012

ASJC Scopus subject areas

  • General Medicine


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