Slight Renal Effect of Mercury from Amalgam Fillings

Serife Eti; Richard Weisman; Robert Hoffman; M. M. Reidenberg

doi:10.1111/j.1600-0773.1995.tb00101.x

Slight Renal Effect of Mercury from Amalgam Fillings

Serife Eti, Richard Weisman, Robert Hoffman, M. M. Reidenberg

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Abstract: The current study was to answer the question: Is enough mercury absorbed from dental amalgam fillings to produce renal damage? One hundred healthy adults (18–44 years old) filled out health questionnaires and voided urine samples. Urine mercury concentration and N‐acetyl‐β‐glucosaminidase (NAG) were measured. Subjects were grouped into those having amalgam fillings (N=66) and those without (N=34). Median (95% Confidence Interval) urine mercury was 1 (1–2) and 0 (0–0.6) ng/ml (P<0.01) and median urine NAG was 23 (18–27) and 16 (11–18) units (P<0.05) in the two groups respectively. People with mercury amalgam fillings excreted slightly more mercury than people without them, and have a very small increase in urinary NAG excretion that is probably of no clinical significance. This dose of mercury absorbed from amalgam appears to be too little to be a public health hazard for renal injury. 1995 Nordic Pharmacological Society

Original language	English (US)
Pages (from-to)	47-49
Number of pages	3
Journal	Pharmacology & Toxicology
Volume	76
Issue number	1
DOIs	https://doi.org/10.1111/j.1600-0773.1995.tb00101.x
State	Published - Jan 1995
Externally published	Yes

ASJC Scopus subject areas

Toxicology
Pharmacology
Health, Toxicology and Mutagenesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1600-0773.1995.tb00101.x

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abstract = "Abstract: The current study was to answer the question: Is enough mercury absorbed from dental amalgam fillings to produce renal damage? One hundred healthy adults (18–44 years old) filled out health questionnaires and voided urine samples. Urine mercury concentration and N‐acetyl‐β‐glucosaminidase (NAG) were measured. Subjects were grouped into those having amalgam fillings (N=66) and those without (N=34). Median (95% Confidence Interval) urine mercury was 1 (1–2) and 0 (0–0.6) ng/ml (P<0.01) and median urine NAG was 23 (18–27) and 16 (11–18) units (P<0.05) in the two groups respectively. People with mercury amalgam fillings excreted slightly more mercury than people without them, and have a very small increase in urinary NAG excretion that is probably of no clinical significance. This dose of mercury absorbed from amalgam appears to be too little to be a public health hazard for renal injury. 1995 Nordic Pharmacological Society",

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AU - Weisman, Richard

AU - Hoffman, Robert

AU - Reidenberg, M. M.

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Y1 - 1995/1

N2 - Abstract: The current study was to answer the question: Is enough mercury absorbed from dental amalgam fillings to produce renal damage? One hundred healthy adults (18–44 years old) filled out health questionnaires and voided urine samples. Urine mercury concentration and N‐acetyl‐β‐glucosaminidase (NAG) were measured. Subjects were grouped into those having amalgam fillings (N=66) and those without (N=34). Median (95% Confidence Interval) urine mercury was 1 (1–2) and 0 (0–0.6) ng/ml (P<0.01) and median urine NAG was 23 (18–27) and 16 (11–18) units (P<0.05) in the two groups respectively. People with mercury amalgam fillings excreted slightly more mercury than people without them, and have a very small increase in urinary NAG excretion that is probably of no clinical significance. This dose of mercury absorbed from amalgam appears to be too little to be a public health hazard for renal injury. 1995 Nordic Pharmacological Society

AB - Abstract: The current study was to answer the question: Is enough mercury absorbed from dental amalgam fillings to produce renal damage? One hundred healthy adults (18–44 years old) filled out health questionnaires and voided urine samples. Urine mercury concentration and N‐acetyl‐β‐glucosaminidase (NAG) were measured. Subjects were grouped into those having amalgam fillings (N=66) and those without (N=34). Median (95% Confidence Interval) urine mercury was 1 (1–2) and 0 (0–0.6) ng/ml (P<0.01) and median urine NAG was 23 (18–27) and 16 (11–18) units (P<0.05) in the two groups respectively. People with mercury amalgam fillings excreted slightly more mercury than people without them, and have a very small increase in urinary NAG excretion that is probably of no clinical significance. This dose of mercury absorbed from amalgam appears to be too little to be a public health hazard for renal injury. 1995 Nordic Pharmacological Society

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Slight Renal Effect of Mercury from Amalgam Fillings

Abstract

ASJC Scopus subject areas

UN SDGs

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