Sleep‐induced nonobstructive hypoventilation associated with diaphragmatic paralysis

Michael J. Thorpy, Wolfgang W. Schmidt‐Nowara, Charles P. Pollak, Elliot D. Weitzman

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


A patient with adult‐onset spinal muscular atrophy causing mild proximal limb muscle weakness had sleep‐induced nonobstructive hypoventilation due to diaphragmatic paralysis. Nocturnal dyspnea and daytime somnolence were associated with frequent arousals from sleep due to arterial oxygen desaturation. The nocturnal use of a cuirass respirator improved the oxygen saturation, resulting in less disrupted sleep, relief of the somnolence, and improved daytime ventilation.

Original languageEnglish (US)
Pages (from-to)308-311
Number of pages4
JournalAnnals of Neurology
Issue number3
StatePublished - Sep 1982

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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