Sleep-disordered breathing in Hispanic/Latino individuals of diverse backgrounds: The Hispanic Community Health Study/Study of Latinos

Susan Redline, Daniela Sotres-Alvarez, Jose Loredo, Martica Hall, Sanjay R. Patel, Alberto Ramos, Neomi Shah, Andrew Ries, Raanan Arens, Janice Barnhart, Marston Youngblood, Phyllis Zee, Martha L. Daviglus

Research output: Contribution to journalArticlepeer-review

184 Scopus citations


Rationale: Hispanic/Latino populations have a high prevalence of cardiovascular risk factors and may be at risk for sleep-disordered breathing (SDB). An understanding of SDB among these populations is needed given evidence that SDB increases cardiovascular risk. Objectives: To quantify SDB prevalence in the U.S. Hispanic/Latino population and its association with symptoms, risk factors, diabetes, and hypertension; and to explore variation by sex and Hispanic/Latino background. Methods: Cross-sectional analysis from the baseline examination of the Hispanic Community Health Study/Study of Latinos. Measurements and Main Results: The apnea-hypopnea index (AHI) was derived from standardized sleep tests; diabetes and hypertension were based on measurement and history. The sample of 14,440 individuals had an age-adjusted prevalence of minimal SDB (AHI≥5), moderateSDB (AHI≥15), and severeSDB (AHI≥30) of 25.8, 9.8, and 3.9%, respectively. Only 1.3% of participants reported a sleep apnea diagnosis. Moderate SDB was associated with being male (adjusted odds ratio, 2.7; 95% confidence interval, 2.3-3.1), obese (16.8; 11.6-24.4), and older. SDB was associated with an increased adjusted odds of impaired glucose tolerance (1.7; 1.3-2.1), diabetes (2.3; 1.8-2.9), and hypertension. The association with hypertension varied across background groups with the strongest associations among individuals of Puerto Rican and Central American background. Conclusions: SDB is prevalent in U.S. Latinos but rarely associated with a clinical diagnosis. Associations with diabetes and hypertension suggest a large burden of disease may be attributed to untreated SDB, supporting the development and evaluation of culturally relevant detection and treatment approaches.

Original languageEnglish (US)
Pages (from-to)335-344
Number of pages10
JournalAmerican journal of respiratory and critical care medicine
Issue number3
StatePublished - Feb 1 2014


  • Disparities
  • Epidemiology
  • Hispanic
  • Sleep-disordered breathing

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine


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