Sirtuins as molecular targets, mediators, and protective agents in metal-induced toxicity

Keyphrases

• Protective Agents 100%
• Deacetylation 100%
• Molecular Targeted Agents 100%
• Metal-induced 100%
• Metal-induced Toxicity 100%
• Intermediary Agent 100%
• Silent Information Regulator 1 (SIRT1) 100%
• Existing Data 66%
• Arsenic 66%
• Nuclear factor-κB 66%
• Cadmium 66%
• Metabolic Disturbances 66%
• Peroxisome Proliferator-activated Receptor-γ coactivator-1α (PGC-1α) 66%
• Sirtuin Signaling 66%
• Manganese 33%
• Oxidative Stress 33%
• Signaling Pathway 33%
• Inflammatory Cytokines 33%
• MEDLINE 33%
• Inflammation 33%
• Low Dose Rate 33%
• Neurotoxicity 33%
• Apoptosis 33%
• Inhibitory Effect 33%
• Overexposure 33%
• Cardiotoxicity 33%
• Increased Vulnerability 33%
• Mercury Hg 33%
• Nephrotoxicity 33%
• Toxic Effects 33%
• Acetylation 33%
• Liver Kinase B1 (LKB1) 33%
• Heavy Metals 33%
• Apoptotic Genes 33%
• Mitochondrial Biogenesis 33%
• Google Scholar 33%
• Copper-iron 33%
• Adverse Health Effects 33%
• Cellular Adhesion Molecules 33%
• Redox Status 33%
• Metal Exposure 33%
• SIRT1 Activity 33%
• P53 Pathway 33%
• Metal Dyshomeostasis 33%
• Cr(VI) 33%
• AMPK Activity 33%
• Hexavalent Chromium 33%
• Metabolic Pathways 33%
• Lead Pb 33%
• SIRT3 33%
• Metal Overload 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Molecular Target 100%
• Protective Agent 100%
• Sirtuin 100%
• Protein P53 40%
• Metabolic Disorder 40%
• Inflammation 20%
• Cytokine 20%
• Neurotoxicity 20%
• Cardiotoxicity 20%
• Nephrotoxicity 20%
• Enzymes 20%
• Heavy Metal 20%
• Hexavalent Chromium 20%
• Cell Adhesion Proteins 20%
• Manganese 20%
• Aluminum 20%